The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
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The Case for Live Attenuated Vaccines against the Neglected Zoonotic Diseases Brucellosis and Bovine TuberculosisVirulence-associated genome mutations of murine rotavirus identified by alternating serial passages in mice and cell cultures.Both haemagglutinin-specific antibody and T cell responses induced by a chimpanzee adenoviral vaccine confer protection against influenza H7N9 viral challenge.Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALB/c mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine.In vitro passage selects for Chlamydia muridarum with enhanced infectivity in cultured cells but attenuated pathogenicity in mouse upper genital tract.Coupling mutagenesis and parallel deep sequencing to probe essential residues in a genome or gene.Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it?Oral vaccines: directed safe passage to the front line of defense.Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure.Worldwide circulation of HSV-2 × HSV-1 recombinant strains.Experimental evolution alters the rate and temporal pattern of population growth in Batrachochytrium dendrobatidis, a lethal fungal pathogen of amphibians.Evolution and medicine in undergraduate education: a prescription for all biology students.Evolutionarily stable attenuation by genome rearrangement in a virus.Genetic stability of Rift Valley fever virus MP-12 vaccine during serial passages in culture cells.Transmissible Viral Vaccines.Arresting Evolution.Viral attenuation by engineered protein fragmentation.Combinatorial Approaches to Viral AttenuationEvolutionary emergence of infectious diseases in heterogeneous host populations
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The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
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article científic
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articolo scientifico
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artigo científico
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artigo científico
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The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
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The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
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The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
@en
The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
@nl
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The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
@en
The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
@nl
P2860
P1476
The double-edged sword: How evolution can make or break a live-attenuated virus vaccine.
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P2093
Kathryn A Hanley
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P2888
P304
P356
10.1007/S12052-011-0365-Y
P577
2011-12-01T00:00:00Z