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A landscape of driver mutations in melanomaSignaling Pathways in MelanogenesisThe involvement of mutant Rac1 in the formation of invadopodia in cultured melanoma cellsMelanoma: oncogenic drivers and the immune systemMultiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic TargetsRare Tumors in Children: Progress Through CollaborationPathways and therapeutic targets in melanomaThe next steps in next-gen sequencing of cancer genomesNUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathwayInsulin-like growth factor system in cancer: novel targeted therapiesUV signaling pathways within the skinFunctional profiling of live melanoma samples using a novel automated platformExtracutaneous melanomas: a primer for the radiologist.HIF1α and HIF2α independently activate SRC to promote melanoma metastasesHAMLET: functional properties and therapeutic potential.Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulationNovel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasisMalignant melanoma and melanocortin 1 receptor.WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors.Isolation and molecular characterization of circulating melanoma cellsKinase fusions are frequent in Spitz tumours and spitzoid melanomas.A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenibA highly recurrent RPS27 5'UTR mutation in melanoma.Adaptive Resistance to Immunotherapy Directed Against p53 Can be Overcome by Global Expression of Tumor-Antigens in Dendritic Cells.Brain neoplasms and coagulation-lessons from heterogeneity.Establishment of HRAS(G12V) transgenic medaka as a stable tumor model for in vivo screening of anticancer drugsNext generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistanceRecombinant adeno-associated virus serotype 6 efficiently transduces primary human melanocytesHydrogels and scaffolds for immunomodulationA novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression.Melanoma genotypes and phenotypes get personal.Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail.Targeting survivin in cancer: novel drug development approaches.Targeting multiple key signaling pathways in melanoma using leelamine.MITF in melanoma: mechanisms behind its expression and activity.S100 proteins in cancer.BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor GrowthButein inhibits metastatic behavior in mouse melanoma cells through VEGF expression and translation-dependent signaling pathway regulation.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
From genes to drugs: targeted strategies for melanoma.
@en
From genes to drugs: targeted strategies for melanoma.
@nl
type
label
From genes to drugs: targeted strategies for melanoma.
@en
From genes to drugs: targeted strategies for melanoma.
@nl
prefLabel
From genes to drugs: targeted strategies for melanoma.
@en
From genes to drugs: targeted strategies for melanoma.
@nl
P356
P1476
From genes to drugs: targeted strategies for melanoma.
@en
P2093
David E Fisher
F Stephen Hodi
P2888
P304
P356
10.1038/NRC3218
P407
P577
2012-04-05T00:00:00Z
P6179
1025395692