Spliceosome and other novel mutations in chronic lymphocytic leukemia and myeloid malignancies.
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Chapter 14: Cancer genome analysisDeriving a mutation index of carcinogenicity using protein structure and protein interfacesA genome-wide aberrant RNA splicing in patients with acute myeloid leukemia identifies novel potential disease markers and therapeutic targets.Pharmacodynamic assays to facilitate preclinical and clinical development of pre-mRNA splicing modulatory drug candidates.SRSF2 Is Essential for Hematopoiesis, and Its Myelodysplastic Syndrome-Related Mutations Dysregulate Alternative Pre-mRNA Splicing.Splicing factor mutations in myelodysplasia.The role of bone marrow biopsy examination at diagnosis of chronic lymphocytic leukemia: a reappraisal.Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.Chronic lymphocytic leukemia: Time to go past genomics?EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.Optimization of antitumor modulators of pre-mRNA splicing.Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia.Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide.Structural and functional analyses of the spliceosome requires a multi-disciplinary approach.A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore.
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Spliceosome and other novel mutations in chronic lymphocytic leukemia and myeloid malignancies.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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name
Spliceosome and other novel mu ...... emia and myeloid malignancies.
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Spliceosome and other novel mu ...... emia and myeloid malignancies.
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Spliceosome and other novel mu ...... emia and myeloid malignancies.
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Spliceosome and other novel mu ...... kemia and myeloid malignancies
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10.1038/LEU.2012.86
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2012-04-09T00:00:00Z
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1004044982