Intramolecular free-radical cyclization reactions on pentose sugars for the synthesis of carba-LNA and carba-ENA and the application of their modified oligonucleotides as potential RNA targeted therapeutics.
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Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid).C5-alkynyl-functionalized α-L-LNA: synthesis, thermal denaturation experiments and enzymatic stabilitySynthesis and characterization of oligodeoxyribonucleotides modified with 2'-amino-α-L-LNA adenine monomers: high-affinity targeting of single-stranded DNALocked nucleic acid (LNA) induced effect on the hybridization and fluorescence properties of oligodeoxyribonucleotides modified with nucleobase-functionalized DNA monomers.C5-amino acid functionalized LNA: positively poised for antisense applications.Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals.Synthesis, duplex stabilization and structural properties of a fluorinated carbocyclic LNA analogueIncorporation of 4'-C-aminomethyl-2'-O-methylthymidine into DNA by thermophilic DNA polymerases.Synthesis and properties of 2'-O,4'-C-spirocyclopropylene bridged nucleic acid (scpBNA), an analogue of 2',4'-BNA/LNA bearing a cyclopropane ring.Synthesis of locked cyclohexene and cyclohexane nucleic acids (LCeNA and LCNA) with modified adenosine units
P2860
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P2860
Intramolecular free-radical cyclization reactions on pentose sugars for the synthesis of carba-LNA and carba-ENA and the application of their modified oligonucleotides as potential RNA targeted therapeutics.
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article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Intramolecular free-radical cy ...... ial RNA targeted therapeutics.
@en
type
label
Intramolecular free-radical cy ...... ial RNA targeted therapeutics.
@en
prefLabel
Intramolecular free-radical cy ...... ial RNA targeted therapeutics.
@en
P356
P1433
P1476
Intramolecular free-radical cy ...... tial RNA targeted therapeutics
@en
P2093
Chuanzheng Zhou
P304
P356
10.1021/CR100306Q
P577
2012-04-24T00:00:00Z