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UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.Mastering tricyclic ring systems for desirable functional cannabinoid activity.AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in miceStrategies for a comprehensive understanding of metabolism by aldehyde oxidase.Pharmaceuticals that contain polycyclic hydrocarbon scaffolds.A simple litmus test for aldehyde oxidase metabolism of heteroarenes.Modern advances in heterocyclic chemistry in drug discovery.Synthesis and biological evaluation of novel farnesylthiosalicylic acid derivatives for cancer treatment.The Isoxazole Ring and Its N-Oxide: A Privileged Core Structure in Neuropsychiatric Therapeutics.Improved Cav2.2 Channel Inhibitors through a gem-Dimethylsulfone Bioisostere Replacement of a Labile Sulfonamide.3-Cyanoallyl boronates are versatile building blocks in the synthesis of polysubstituted thiophenes.Access to a new class of synthetic building blocks via trifluoromethoxylation of pyridines and pyrimidines.CO2-promoted oxidative cross-coupling reaction for C-S bond formation via masked strategy in an odourless way.Enantioselective Synthesis of Oxetanes Bearing All-Carbon Quaternary Stereocenters via Iridium-Catalyzed C-C Bond-Forming Transfer Hydrogenation.Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Mitigating heterocycle metabolism in drug discovery.
@en
type
label
Mitigating heterocycle metabolism in drug discovery.
@en
prefLabel
Mitigating heterocycle metabolism in drug discovery.
@en
P356
P1476
Mitigating heterocycle metabolism in drug discovery.
@en
P2093
Christopher Fotsch
David J St Jean
P304
P356
10.1021/JM300343M
P407
P577
2012-05-07T00:00:00Z