Strategies for the enantioselective synthesis of spirooxindoles.
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Therapeutic Potential of Spirooxindoles as Antiviral AgentsOne-pot four-component reaction for convenient synthesis of functionalized 1-benzamidospiro[indoline-3,4'-pyridines].Construction of a spirooxindole amide library through nitrile hydrozirconation-acylation-cyclization cascade.Regio- and stereoselective synthesis of spirooxindole 1'-nitro pyrrolizidines with five concurrent stereocenters under aqueous medium and their bioprospection using the zebrafish (Danio rerio) embryo model.Squaramide-Catalyzed Synthesis of Enantioenriched Spirocyclic Oxindoles via Ketimine Intermediates with Multiple Active Sites.Synthesis of functionalized spiro[indoline-3,4'-pyridines] and spiro[indoline-3,4'-pyridinones] via one-pot four-component reactions.Facile synthesis of functionalized spiro[indoline-3,2'-oxiran]-2-ones by Darzens reactionEnantioselective Synthesis of Spirooxindole Enols: Regioselective and Asymmetric [3+2] Cyclization of 3-Isothiocyanato Oxindoles with Dibenzylidene Ketones.Synthesis of spiro[indoline-3,1'-quinolizines] and spiro[indoline-3, 4'-pyrido[1,2-a]quinolines] via three-component reactions of azaarenes, acetylenedicarboxylate, and 3-methyleneoxindoles.Formation of diverse polycyclic spirooxindoles via three-component reaction of isoquinolinium salts, isatins and malononitrileAdditive-assisted regioselective 1,3-dipolar cycloaddition of azomethine ylides with benzylideneacetoneRecent advances in organocatalytic methods for asymmetric C-C bond formation.Strategies for the asymmetric functionalization of indoles: an update.Molecular Hybridization-Guided One-Pot Multicomponent Synthesis of Turmerone Motif-Fused 3,3'-Pyrrolidinyl-dispirooxindoles via a 1,3-Dipolar Cycloaddition Reaction.Spiro-oxindoles as a Promising Class of Small Molecule Inhibitors of p53-MDM2 Interaction Useful in Targeted Cancer Therapy.Transition-Metal-Free Synthesis of N-Hydroxy Oxindoles by an Aza-Nazarov-Type Reaction Involving Azaoxyallyl Cations.Construction of highly enantioenriched spirocyclopentaneoxindoles containing four consecutive stereocenters via thiourea-catalyzed asymmetric Michael-Henry cascade reactions.Streocontrolled construction of six vicinal stereogenic centers on spiropyrazolones via organocascade Michael/Michael/1,2-addition reactions.Organocatalytic Asymmetric Domino Michael/Henry Reaction of Indolin-3-ones with o-Formyl-β-nitrostyrenes.Copper(II)- and palladium(II)-catalyzed enantioselective Claisen rearrangement of allyloxy- and propargyloxy-indoles to quaternary oxindoles and spirocyclic lactones.Enantioselective cyclization of enamide-ynes and application to the synthesis of the kopsifoline coreCatalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones.Asymmetric domino synthesis of indanes bearing four contiguous stereocentres catalyzed by sub-mol% loadings of a squaramide in minutes.Titanium(IV)-catalyzed stereoselective synthesis of spirooxindole-1-pyrrolines.Acyl Radicals from Aromatic Carboxylic Acids by Means of Visible-Light Photoredox Catalysis.Combining silver- and organocatalysis: an enantioselective sequential catalytic approach towards pyrano-annulated pyrazoles.Organocatalytic diastereo- and enantioselective 1,3-dipolar cycloaddition of azlactones and methyleneindolinones.Catalytic [4+2] cyclization of α,β-unsaturated acyl chlorides with 3-alkylenyloxindoles: highly diastereo- and enantioselective synthesis of spirocarbocyclic oxindoles.Convergent approach to complex spirocyclic pyrans: practical synthesis of the oxa-pinnaic acid core.Enantioselective construction of spirooxindole derivatives through [3+2] annulation catalyzed by a bisthiourea as a multiple-hydrogen-bond donor.Cinchona-based squaramide-catalysed cascade aza-Michael-Michael addition: enantioselective construction of functionalized spirooxindole tetrahydroquinolines.Highly efficient construction of bisspirooxindoles containing vicinal spirocenters through an organocatalytic modified Feist-Bénary reaction.Control of remote stereochemistry in the synthesis of spirocyclic oxindoles: vinylogous organocascade catalysis.Copper-catalyzed oxidative benzylarylation of acrylamides by benzylic C-H bond functionalization for the synthesis of oxindoles.Counterion effects in the catalytic stereoselective synthesis of 2,3'-pyrrolidinyl spirooxindoles.Asymmetric Synthesis of All-Carbon Quaternary Spirocycles via a Catalytic Enantioselective Allylic Alkylation Strategy.Baylis-Hillman bromides as a source of 1,3-dipoles: sterically directed synthesis of oxindole-fused spirooxirane and spirodihydrofuran frameworks.Facile synthesis of aza-spirocyclopropanyl oxindoles by the reaction of 3-(2-bromoethyl)-indole with 2,3-dimethylimidazole-1-sulfonyl azide triflate.NHC-catalyzed [4+2] cycloaddition reactions for the synthesis of 3'-spirocyclic oxindoles via a C-F bond cleavage protocol.Synthesis of functionalized dispiro[indoline-3,1[Formula: see text]-cyclopentane-3[Formula: see text],3[Formula: see text]-indolines] via cyclodimerization of 3-phenacylideneoxindolines with benzoylhydrazides and arylhydrazines.
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Strategies for the enantioselective synthesis of spirooxindoles.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Strategies for the enantioselective synthesis of spirooxindoles.
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type
label
Strategies for the enantioselective synthesis of spirooxindoles.
@en
prefLabel
Strategies for the enantioselective synthesis of spirooxindoles.
@en
P2093
P2860
P356
P1476
Strategies for the enantioselective synthesis of spirooxindoles.
@en
P2093
Annaliese K Franz
Joseph J Badillo
Nicolas R Ball-Jones
P2860
P304
P356
10.1039/C2OB25184A
P577
2012-05-14T00:00:00Z