Merlin, a multi-suppressor from cell membrane to the nucleus.
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Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt SignallingMerlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury.Tumor suppressor Nf2/merlin drives Schwann cell changes following electromagnetic field exposure through Hippo-dependent mechanisms.p75NTR is highly expressed in vestibular schwannomas and promotes cell survival by activating nuclear transcription factor κB.A deletion causing NF2 exon 9 skipping is associated with familial autosomal dominant intramedullary ependymoma.NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations.Recurrent chromosome 22 deletions in osteoblastoma affect inhibitors of the Wnt/beta-catenin signaling pathway.Neurofibromatosis-related tumors: emerging biology and therapies.Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progressionThe hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy.Merlin, the NF2 gene product.Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours.Artesunate induces necrotic cell death in schwannoma cells.Functional interdependence of NHE1 and merlin in human melanoma cells.Re-evaluation of cytostatic therapies for meningiomas in vitro.The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cellsMeningioma.Muscle action potential scans and ultrasound imaging in neurofibromatosis type 2.Mutations affecting BRAF, EGFR, PIK3CA, and KRAS are not associated with sporadic vestibular schwannomas.
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Merlin, a multi-suppressor from cell membrane to the nucleus.
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Merlin, a multi-suppressor from cell membrane to the nucleus.
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Merlin, a multi-suppressor from cell membrane to the nucleus.
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Merlin, a multi-suppressor from cell membrane to the nucleus.
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Merlin, a multi-suppressor from cell membrane to the nucleus.
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C Oliver Hanemann
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10.1016/J.FEBSLET.2012.03.016
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2012-03-21T00:00:00Z