Allostery and binding cooperativity of the catalytic subunit of protein kinase A by NMR spectroscopy and molecular dynamics simulations.
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PKA: lessons learned after twenty yearsDynamics-Driven Allostery in Protein KinasesAllosteric coupling between the intracellular coupling helix 4 and regulatory sites of the first nucleotide-binding domain of CFTRStructure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.Exploring Molecular Mechanisms of Paradoxical Activation in the BRAF Kinase Dimers: Atomistic Simulations of Conformational Dynamics and Modeling of Allosteric Communication Networks and Signaling Pathways.NMR mapping of protein conformational landscapes using coordinated behavior of chemical shifts upon ligand binding.Pseudokinases from a structural perspectiveMapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation FactorsConformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations.Solution NMR Spectroscopy for the Study of Enzyme Allostery.Role of conformational entropy in the activity and regulation of the catalytic subunit of protein kinase A.Prediction of the repeat domain structures and impact of parkinsonism-associated variations on structure and function of all functional domains of leucine-rich repeat kinase 2 (LRRK2).Information flow and protein dynamics: the interplay between nuclear magnetic resonance spectroscopy and molecular dynamics simulations.Uncoupling Catalytic and Binding Functions in the Cyclic AMP-Dependent Protein Kinase AA QM/MM study of Kemptide phosphorylation catalyzed by protein kinase A. The role of Asp166 as a general acid/base catalyst.Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activityBinding mechanism and dynamic conformational change of C subunit of PKA with different pathways.
P2860
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P2860
Allostery and binding cooperativity of the catalytic subunit of protein kinase A by NMR spectroscopy and molecular dynamics simulations.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Allostery and binding cooperat ...... olecular dynamics simulations.
@en
type
label
Allostery and binding cooperat ...... olecular dynamics simulations.
@en
prefLabel
Allostery and binding cooperat ...... olecular dynamics simulations.
@en
P2093
P2860
P1476
Allostery and binding cooperat ...... molecular dynamics simulations
@en
P2093
Gianluigi Veglia
Larry R Masterson
P2860
P304
P356
10.1016/B978-0-12-398312-1.00012-3
P577
2012-01-01T00:00:00Z