Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy.
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KIFC1: a promising chemotherapy target for cancer treatment?Heading off with the herd: how cancer cells might maneuver supernumerary centrosomes for directional migrationThe more the messier: centrosome amplification as a novel biomarker for personalized treatment of colorectal cancersRecent findings and future directions for interpolar mitotic kinesin inhibitors in cancer therapyDocetaxel-induced polyploidization may underlie chemoresistance and disease relapsePrevention effect of rare ginsenosides against stress-hormone induced MTOC amplificationInduction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach.Centrosome Aberration Frequency and Disease Association in B-Acute Lymphoblastic Leukemia.KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries.Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis.Centrosome-declustering drugs mediate a two-pronged attack on interphase and mitosis in supercentrosomal cancer cells.Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Amplified centrosomes may underlie aggressive disease course in pancreatic ductal adenocarcinoma.KIFC1 is a novel potential therapeutic target for breast cancer.Erroneous Silencing of the Mitotic Checkpoint by Aberrant Spindle Pole-Kinetochore Coordination.Multinucleation and Mesenchymal-to-Epithelial Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate CancerTurning the headlights on novel cancer biomarkers: Inspection of mechanics underlying intratumor heterogeneityCell death associated with abnormal mitosis observed by confocal imaging in live cancer cells.Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes.Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancerThe centrosome as potential target for cancer therapy and prevention.Interphase microtubules: chief casualties in the war on cancer?New Colchicine-Derived Triazoles and Their Influence on Cytotoxicity and Microtubule Morphology.Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.Centrosome amplification: a suspect in breast cancer and racial disparities.Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines.Quantitative multi-parametric evaluation of centrosome declustering drugs: centrosome amplification, mitotic phenotype, cell cycle and deathC-terminal kinesin motor KIFC1 participates in facilitating proper cell division of human seminomaExclusive destruction of mitotic spindles in human cancer cells.A look into centrosome abnormalities in colon cancer cells, how they arise and how they might be targeted therapeutically.The resveratrol analogue trimethoxystilbene inhibits cancer cell growth by inducing multipolar cell mitosis.KIFC1, a novel potential prognostic factor and therapeutic target in hepatocellular carcinoma.
P2860
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P2860
Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Let's huddle to prevent a mudd ...... ttractive anticancer strategy.
@en
type
label
Let's huddle to prevent a mudd ...... ttractive anticancer strategy.
@en
prefLabel
Let's huddle to prevent a mudd ...... ttractive anticancer strategy.
@en
P2093
P2860
P356
P1476
Let's huddle to prevent a mudd ...... ttractive anticancer strategy.
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2012.61
P577
2012-06-01T00:00:00Z