Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.
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Ten things you should know about protein kinases: IUPHAR Review 14The AMPK agonist AICAR inhibits TGF-β1 induced activation of kidney myofibroblastsInhibition of Extracellular Calcium Influx Results in Enhanced IL-12 Production in LPS-Treated Murine Macrophages by Downregulation of the CaMKKβ-AMPK-SIRT1 Signaling PathwayAnti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease.Hematopoietic tissue factor-protease-activated receptor 2 signaling promotes hepatic inflammation and contributes to pathways of gluconeogenesis and steatosis in obese mice.Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice.Obesity and asthma in children: current and future therapeutic optionsGlycolytic switch in response to betulinic acid in non-cancer cellsTriggering receptor expressed on myeloid cells and 5'adenosine monophosphate-activated protein kinase in the inflammatory response: a potential therapeutic target.Resveratrol suppresses PAI-1 gene expression in a human in vitro model of inflamed adipose tissue.Effects of an High-Fat Diet Enriched in Lard or in Fish Oil on the Hypothalamic Amp-Activated Protein Kinase and Inflammatory Mediators.A marriage of two "Methusalem" drugs for the treatment of psoriasis?: Arguments for a pilot trial with metformin as add-on for methotrexate.Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury.Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487.Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation.Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms.Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cellsEndogenous AMPK acts as a detrimental factor in fulminant hepatitis via potentiating JNK-dependent hepatocyte apoptosis.Mitochondrial dysfunction: a basic mechanism in inflammation-related non-communicable diseases and therapeutic opportunities.The AMPK enzyme-complex: from the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders.Small molecules as therapy for uveitis: a selected perspective of new and developing agents.Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activation.Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase.Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System.Cellular stress response mechanisms as therapeutic targets of ginsenosides.Metformin use and asthma outcomes among patients with concurrent asthma and diabetes.AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis.5-Aminoimidazole-4-carboxamide ribonucleoside-mediated adenosine monophosphate-activated protein kinase activation induces protective innate responses in bacterial endophthalmitis.Searching for biomarkers of comorbidities in sera of treated HIV-infected patients by isoelectric focusing.Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitisCNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models.Regulation of neuroinflammation by matrix metalloproteinase-8 inhibitor derivatives in activated microglia and astrocytes.Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia.AMPK and cardiac remodelling.Toxicity of a novel therapeutic agent targeting mitochondrial complex I.Green tea extract intake during lactation modified cardiac macrophage infiltration and AMP-activated protein kinase phosphorylation in weanling rats from undernourished mother during gestation and lactation.Molecular action of isoflavone genistein in the human epithelial cell line HaCaT.A concise review on advances in development of small molecule anti-inflammatory therapeutics emphasising AMPK: An emerging target.
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P2860
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.
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article científic
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article scientifique
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articol științific
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articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.
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type
label
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.
@en
prefLabel
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.
@en
P2860
P1476
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation
@en
P2093
Timothy M Palmer
P2860
P304
P356
10.1517/13543784.2012.696609
P407
P50
P577
2012-06-14T00:00:00Z