Initiation of HIV-1 reverse transcription and functional role of nucleocapsid-mediated tRNA/viral genome interactions.
about
Methylated nucleosides in tRNA and tRNA methyltransferasesHIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus.Efficient HIV-1 inhibition by a 16 nt-long RNA aptamer designed by combining in vitro selection and in silico optimisation strategies.Similarities and differences in the nucleic acid chaperone activity of HIV-2 and HIV-1 nucleocapsid proteins in vitroSelection of fully processed HIV-1 nucleocapsid protein is required for optimal nucleic acid chaperone activity in reverse transcription.Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy.The Interaction between tRNA(Lys) 3 and the primer activation signal deciphered by NMR spectroscopy.A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.Heterogeneous structures formed by conserved RNA sequences within the HIV reverse transcription initiation site.Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition.The design of RNA binders: targeting the HIV replication cycle as a case study.Insights into the mechanisms of RNA secondary structure destabilization by the HIV-1 nucleocapsid protein.HIV-1 Pr55Gag binds genomic and spliced RNAs with different affinity and stoichiometry.Requirements for nucleocapsid-mediated regulation of reverse transcription during the late steps of HIV-1 assembly.Role of the primer activation signal in tRNA annealing onto the HIV-1 genome studied by single-molecule FRET microscopy.Structural insight into HIV-1 reverse transcription initiation in MAL-like templates (CRF01_AE, subtype G and CRF02_AG).1H, 13C and 15N backbone and partial side-chain resonance assignments of the C-terminal domain of HIV-1 Pr55Gag encompassed in NCp15.
P2860
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P2860
Initiation of HIV-1 reverse transcription and functional role of nucleocapsid-mediated tRNA/viral genome interactions.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Initiation of HIV-1 reverse tr ...... RNA/viral genome interactions.
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type
label
Initiation of HIV-1 reverse tr ...... RNA/viral genome interactions.
@en
prefLabel
Initiation of HIV-1 reverse tr ...... RNA/viral genome interactions.
@en
P50
P1433
P1476
Initiation of HIV-1 reverse tr ...... RNA/viral genome interactions.
@en
P2093
Dona Sleiman
Valérie Goldschmidt
P304
P356
10.1016/J.VIRUSRES.2012.06.006
P577
2012-06-18T00:00:00Z