Opening the floodgates: proteomics and the integrin adhesome.
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Adhesion protein networks reveal functions proximal and distal to cell-matrix contactsIntegrin cytoplasmic tail interactionsDisentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix AdhesionsNBR1 enables autophagy-dependent focal adhesion turnoverPlasticity in the macromolecular-scale causal networks of cell migrationThe integrin adhesome network at a glanceA multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin.A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting.Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules.Coordination between Intra- and Extracellular Forces Regulates Focal Adhesion Dynamics.Symmetric exchange of multi-protein building blocks between stationary focal adhesions and the cytosol.The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activationPre-metazoan origins and evolution of the cadherin adhesome.Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassemblyRac1-dependent phosphorylation and focal adhesion recruitment of myosin IIA regulates migration and mechanosensing.Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells.Highly Multiplexed Imaging Uncovers Changes in Compositional Noise within Assembling Focal AdhesionsProteomic analysis of integrin-associated complexes from mesenchymal stem cellsConversion of nanoscale topographical information of cluster-assembled zirconia surfaces into mechanotransductive events promotes neuronal differentiationLoss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness.Plectin-containing, centrally localized focal adhesions exert traction forces in primary lung epithelial cells.Scale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive Pathways.Dynamic regulation of the structure and functions of integrin adhesions.Protein kinase C, focal adhesions and the regulation of cell migration.Regulation of cell-matrix adhesion by OLA1, the Obg-like ATPase 1.The contribution of vascular smooth muscle to aortic stiffness across length scales.Actin in action: imaging approaches to study cytoskeleton structure and function.Integrative systems and synthetic biology of cell-matrix adhesion sites.Quantitative profiling of spreading-coupled protein tyrosine phosphorylation in migratory cells.Multiplexed imaging of intracellular protein networks.Molecular Targeting of Integrins and Integrin-Associated Signaling Networks in Radiation Oncology.Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling.Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site.A proteomics view on integrin-mediated adhesions.Proximity biotinylation provides insight into the molecular composition of focal adhesions at the nanometer scale.SnapShot: talin and the modular nature of the integrin adhesome.Job-splitting among integrins.Visualizing the interior architecture of focal adhesions with high-resolution traction maps.Computational modeling of single-cell mechanics and cytoskeletal mechanobiology.
P2860
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P2860
Opening the floodgates: proteomics and the integrin adhesome.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Opening the floodgates: proteomics and the integrin adhesome.
@en
type
label
Opening the floodgates: proteomics and the integrin adhesome.
@en
prefLabel
Opening the floodgates: proteomics and the integrin adhesome.
@en
P1476
Opening the floodgates: proteomics and the integrin adhesome.
@en
P2093
Ronen Zaidel-Bar
Tamar Geiger
P304
P356
10.1016/J.CEB.2012.05.004
P577
2012-06-22T00:00:00Z