Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders.
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Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritisLegal highs: staying on top of the flood of novel psychoactive substancesMetabolic effects of smoking cessationCannabinoids, eating behaviour, and energy homeostasis.Rimonabant improves metabolic parameters partially attributed to restoration of high voltage-activated Ca2+ channels in skeletal muscle in HFD-fed miceNew insights on the role of the endocannabinoid system in the regulation of energy balance.(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons.Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicityControlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes.The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesityChronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese menThe endocannabinoid system in advanced liver cirrhosis: pathophysiological implication and future perspectives.Peripheral targets in obesity treatment: a comprehensive update.The endocannabinoid system and appetite: relevance for food reward.New perspectives on the development of antiobesity drugs.Developmental programming of somatic growth, behavior and endocannabinoid metabolism by variation of early postnatal nutrition in a cross-fostering mouse model.A novel live cell assay to measure diacylglycerol lipase α activityNovel Peripherally Restricted Cannabinoid 1 Receptor Selective Antagonist TXX-522 with Prominent Weight-Loss Efficacy in Diet Induced Obese Mice.Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole quinuclidine analogs.Metabolic Profiling of CB1 Neutral Antagonists.Hypothalamic miR-219 regulates individual metabolic differences in response to diet-induced weight cycling.Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects.LH-21, A Peripheral Cannabinoid Receptor 1 Antagonist, Exerts Favorable Metabolic Modulation Including Antihypertensive Effect in KKAy Mice by Regulating Inflammatory Cytokines and Adipokines on Adipose Tissue.
P2860
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P2860
Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Second generation CB1 receptor ...... e against metabolic disorders.
@en
type
label
Second generation CB1 receptor ...... e against metabolic disorders.
@en
prefLabel
Second generation CB1 receptor ...... e against metabolic disorders.
@en
P2860
P1476
Second generation CB1 receptor ...... e against metabolic disorders.
@en
P2860
P304
P356
10.1517/13543784.2012.704019
P407
P577
2012-07-11T00:00:00Z