Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5 - Wikidata - awgldk - TriplyDB

Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5

Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5

http://www.wikidata.org/entity/Q38026611

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Tumor progression locus 2 (Tpl2) kinase as a novel therapeutic target for cancer: double-sided effects of Tpl2 on cancer Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5).In silico identification of potential key regulatory factors in smoking-induced lung cancer.Up-regulated microRNA499a by hepatitis B virus induced hepatocellular carcinogenesis via targeting MAPK6 Down-regulation of SerpinB2 is associated with gefitinib resistance in non-small cell lung cancer and enhances invadopodia-like structure protrusions.Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1.Cross-talk between the circadian clock and the cell cycle in cancer.The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation.A regulatory BMI1/let-7i/ERK3 pathway controls the motility of head and neck cancer cells MAPK6/MAPK4 signaling L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.p-S MAPK6 phosphorylates NCOA3 p-S857 NCOA3:ETV4 bind MMP2 and MMP10 promoter p-S MAPK6;4:p-T182 MAPKAPK5 translocate to the cytosol p-S MAPKAPK5 phosphorylates HSPB1 p-T182 MAPKAPK5 phosphorylates FOXO3 p-S215 FOXO3 translocates to the nucleus MYC mRNA translation is negatively regulated by miR-34B and C MYC positively regulates MAPKAPK5 gene expression IGF2BP1 binds MAPK4 mRNA IGF2BP1 represses translation of MAPK4 mRNA The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture.

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Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5

http://www.wikidata.org/entity/Q38026611

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Tumour promoting and suppressi ...... signalling pathway ERK3/4-MK5

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Journal of Molecular Signaling

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Tumour promoting and suppressi ...... signalling pathway ERK3/4-MK5

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Gianina Dumitriu

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Sergiy Kostenko

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Ugo Moens

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P2860

p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance

The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis

PRAK is essential for ras-induced senescence and tumor suppression

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation

The RSK family of kinases: emerging roles in cellular signalling

MSK activation and physiological roles

Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway

PRAK, a novel protein kinase regulated by the p38 MAP kinase

RNA-binding IMPs promote cell adhesion and invadopodia formation.

N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome

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9

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scholarly article

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10.1186/1750-2187-7-9

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1

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7

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2012-07-16T00:00:00Z

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229154663

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22800433

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3419095

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