Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.
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Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismMyeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer ChemotherapyDynamics of double strand breaks and chromosomal translocationsUse of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.Destruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain gliomaA "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.Molecular signature of anastasis for reversal of apoptosis.Topoisomerase II and leukemia.Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons.Topoisomerase-mediated chromosomal break repair: an emerging player in many games.TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcriptionChemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells.Clonal evolution in therapy-related neoplasms.The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.Etoposide quinone is a covalent poison of human topoisomerase IIβ.Flat cells come full sphere: Are mutant cytoskeletal-related proteins oncoprotein-monsters or useful immunogens?Intraventricular etoposide safety and toxicity profile in children and young adults with refractory or recurrent malignant brain tumors.Do transcription factories and TOP2B provide a recipe for chromosome translocations in therapy-related leukemia?Yi-qi-yang-yin-tang increases the sensitivity of KG1a leukemia stem cells to daunorubicin by promoting cell cycle progression and regulating the expression of PTEN, TOPOII and mTOR.Lomefloxacin Induces Oxidative Stress and Apoptosis in COLO829 Melanoma Cells.Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia†Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry.Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7.Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences.Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context.Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβTOP2B: The First Thirty Years
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Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Mechanism of generation of the ...... anti-topoisomerase II agents.
@en
type
label
Mechanism of generation of the ...... anti-topoisomerase II agents.
@en
prefLabel
Mechanism of generation of the ...... anti-topoisomerase II agents.
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P2860
P921
P356
P1476
Mechanism of generation of the ...... o anti-topoisomerase II agents
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P2093
Caroline A Austin
Ian G Cowell
P2860
P304
P356
10.3390/IJERPH9062075
P5008
P577
2012-05-31T00:00:00Z