Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania. - Wikidata - awgldk - TriplyDB

Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.

Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.

http://www.wikidata.org/entity/Q38031615

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Genomic confirmation of hybridisation and recent inbreeding in a vector-isolated Leishmania population The mating competence of geographically diverse Leishmania major strains in their natural and unnatural sand fly vectors Population structure and evidence for both clonality and recombination among Brazilian strains of the subgenus Leishmania (Viannia)Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans Plasticity of the Leishmania genome leading to gene copy number variations and drug resistance Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones Sex is a ubiquitous, ancient, and inherent attribute of eukaryotic life Comparative genomics of canine-isolated Leishmania (Leishmania) amazonensis from an endemic focus of visceral leishmaniasis in Governador Valadares, southeastern Brazil.Genetic metabolic complementation establishes a requirement for GDP-fucose in Leishmania.Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strain.Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB.Generators of phenotypic diversity in the evolution of pathogenic microorganisms.Putative panmixia in restricted populations of Trypanosoma cruzi isolated from wild Triatoma infestans in Bolivia.The genome of Leishmania panamensis: insights into genomics of the L. (Viannia) subgenus.The past, present, and future of Leishmania genomics and transcriptomics.The nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in trypanosomatids Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis.Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches.LmHus1 is required for the DNA damage response in Leishmania major and forms a complex with an unusual Rad9 homologue.Ploidy dynamics and evolvability in fungi The genome sequence of Leishmania (Leishmania) amazonensis: functional annotation and extended analysis of gene models Comparative analyses of whole genome sequences of Leishmania infantum isolates from humans and dogs in northeastern Brazil.Constitutive aneuploidy and genomic instability in the single-celled eukaryote Giardia intestinalis.Comparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity.Relationship of genetic causes and inhibin B in non obstructive azoospermia spermatogenic failure.Genetic variation in RPOIILS gene encoding RNA polymerase II largest subunit from Leishmania major.Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani.Genome Plasticity in Cultured : Comparison of Early and Late Passages Resistance of Leishmania infantum to allopurinol is associated with chromosome and gene copy number variations including decrease in the S-adenosylmethionine synthetase (METK) gene copy number

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Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.

http://www.wikidata.org/entity/Q38031615

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artikel ilmiah

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Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.

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Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.

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Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania.

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J.1365-2958.2012.08185.X

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Molecular Microbiology

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Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania

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Laurence Lachaud

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Lucien Crobu

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Michel Pagès

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Nathalie Bourgeois

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Yvon Sterkers

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P2860

Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

Leishmaniasis impact and treatment access

Comparative genomics of trypanosomatid parasitic protozoa

Conserved linkage groups associated with large-scale chromosomal rearrangements between Old World and New World Leishmania genomes.

Effect of large targeted deletions on the mitotic stability of an extra chromosome mediating drug resistance in Leishmania.

The switch region on Leishmania major chromosome 1 is not required for mitotic stability or gene expression, but appears to be essential.

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.

Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species.

Experimental studies on ploidy evolution in yeast.

Plasticity in chromosome number and testing of essential genes in Leishmania by targeting.

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15-23

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scholarly article

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10.1111/J.1365-2958.2012.08185.X

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Patrick Bastien

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230614600

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22857263

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