Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
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The molecular targets of approved treatments for pulmonary arterial hypertensionPerspective: ambient air pollution: inflammatory response and effects on the lung's vasculatureInhibition of ENaC by endothelin-1Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsHeme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factorOrphan nuclear receptor Nur77 is a novel negative regulator of endothelin-1 expression in vascular endothelial cells.Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitudeTissue-specific and time-dependent regulation of the endothelin axis by the circadian clock protein Per1.Pulmonary arterial hypertension: basis of sex differences in incidence and treatment response.Endothelin-1 suppresses insulin-stimulated Akt phosphorylation and glucose uptake via GPCR kinase 2 in skeletal muscle cells.Is there evidence for vasculitis in systemic sclerosis?Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.Endothelin receptor polymorphisms in the cardiovascular system: potential implications for therapy and screening.Current state of endothelin receptor antagonism in hypertension and pulmonary hypertension.Macitentan: a review of its use in patients with pulmonary arterial hypertension.Pharmacokinetic and pharmacodynamic evaluation of macitentan , a novel endothelin receptor antagonist for the treatment of pulmonary arterial hypertension.Beyond vasodilator: anti-apoptotic effect of endothelin receptor antagonist.Systematic Review of Randomized Controlled Trials of Endothelin Receptor Antagonists for Pulmonary Arterial Hypertension.Beyond the evidence: treating pulmonary hypertension in the intensive care unit.Protective effects of ginaton on vascular endothelial cells injured by angiotensin II and hypoxia in vitro.Protection of vascular endothelial cells injured by angiotensin II and hypoxia in vitro by Ginkgo biloba (Ginaton).Pentose Shunt, Glucose-6-Phosphate Dehydrogenase, NADPH Redox, and Stem Cells in Pulmonary Hypertension.Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple-dose study in healthy subjects.Rho kinase and Na+ /H+ exchanger mediate endothelin-1-induced pulmonary arterial smooth muscle cell proliferation and migration.
P2860
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P2860
Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
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article científic
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articolo scientifico
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artigo científico
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name
Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
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type
label
Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
@en
prefLabel
Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
@en
P1433
P1476
Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
@en
P2093
Lewis J Rubin
P304
P356
10.1016/J.LFS.2012.07.033
P407
P577
2012-08-03T00:00:00Z