An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity
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Neural and mesenchymal stem cells in animal models of Huntington's disease: past experiences and future challengesResveratrol: A Focus on Several Neurodegenerative DiseasesIntermediate phenotypes and biomarkers of treatment outcome in major depressive disorderIron dysregulation in Huntington's diseaseHuman-to-mouse prion-like propagation of mutant huntingtin protein.Assessment of motor function, sensory motor gating and recognition memory in a novel BACHD transgenic rat model for huntington disease.Free-Energy Landscape of the Amino-Terminal Fragment of Huntingtin in Aqueous SolutionProbing the Huntingtin 1-17 membrane anchor on a phospholipid bilayer by using all-atom simulationsThe dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell modelExpression of RNAs Coding for Metal Transporters in Blood of Patients with Huntington's DiseaseQuantitative Electroencephalographic Biomarkers in Preclinical and Human Studies of Huntington's Disease: Are They Fit-for-Purpose for Treatment Development?Pharmacological protein targets in polyglutamine diseases: mutant polypeptides and their interactors.Phenotypic screens targeting neurodegenerative diseases.Studying neurodegenerative diseases in culture models.The fate of cell grafts for the treatment of Huntington's disease: the post-mortem evidence.Is Huntington's disease a tauopathy?A link between chromatin condensation mechanisms and Huntington's disease: connecting the dots.Proteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease.Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status.D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells.Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.Moving toward a gene therapy for Huntington's disease.Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology.RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes.The Role of Gene Editing in Neurodegenerative Diseases.Current Screening Methodologies in Drug Discovery for Selected Human Diseases
P2860
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P2860
An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
An in vitro perspective on the ...... nt huntingtin protein toxicity
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type
label
An in vitro perspective on the ...... nt huntingtin protein toxicity
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prefLabel
An in vitro perspective on the ...... nt huntingtin protein toxicity
@en
P2860
P356
P1476
An in vitro perspective on the ...... nt huntingtin protein toxicity
@en
P2093
F Cicchetti
P2860
P356
10.1038/CDDIS.2012.121
P577
2012-08-30T00:00:00Z