Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.
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A highly sensitive targeted mass spectrometric assay for quantification of AGR2 protein in human urine and serumAGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucusQuantitative Shotgun Proteomics Unveils Candidate Novel Esophageal Adenocarcinoma (EAC)-specific Proteins.Analysis of the transcriptome in hyperoxic lung injury and sex-specific alterations in gene expression.Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells.Generalized portrait of cancer metabolic pathways inferred from a list of genes overexpressed in cancerThe promise of perfect adult tissue repair and regeneration in mammals: Learning from regenerative amphibians and fish.Knockdown of anterior gradient 2 expression extenuates tumor-associated phenotypes of SNU-478 ampulla of Vater cancer cells.Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein.Genes dysregulated to different extent or oppositely in estrogen receptor-positive and estrogen receptor-negative breast cancers.A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG)AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection.Anterior gradient protein 3 is associated with less aggressive tumors and better outcome of breast cancer patients.Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition.Mechanism of Action of Secreted Newt Anterior Gradient ProteinHigh expression of AGR2 in lung cancer is predictive of poor survival.Secretion of protein disulphide isomerase AGR2 confers tumorigenic propertiesBladder cancer cells secrete while normal bladder cells express but do not secrete AGR2.Cancer-secreted AGR2 induces programmed cell death in normal cells.AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.Conjugation of gold nanoparticles and recombinant human endostatin modulates vascular normalization via interruption of anterior gradient 2-mediated angiogenesis.Splice variant transcripts of the anterior gradient 2 gene as a marker of prostate cancer.Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2.Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines.Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition.ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation.Emerging roles of protein disulfide isomerase in cancer.The prognostic value of AGR2 expression in solid tumours: a systematic review and meta-analysis.Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization.FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.The sequence-specific peptide-binding activity of the protein sulfide isomerase AGR2 directs its' stable binding to the oncogenic receptor EpCAM.Tamoxifen-Dependent Induction of AGR2 Is Associated with Increased Aggressiveness of Endometrial Cancer Cells.Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle.
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Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.
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type
label
Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.
@en
prefLabel
Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development.
@en
P2093
P2860
P356
P1433
P1476
Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development
@en
P2093
B Vojtesek
P2860
P2888
P304
P356
10.1038/ONC.2012.346
P407
P577
2012-09-03T00:00:00Z
P5875
P6179
1022908646