The future of glycoprotein VI as an antithrombotic target.
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Cross-Linking GPVI-Fc by Anti-Fc Antibodies Potentiates Its Inhibition of Atherosclerotic Plaque- and Collagen-Induced Platelet ActivationAnti-GPVI Fab SAR264565 effectively blocks GPVI function in ex vivo human platelets under arterial shear in a perfusion chamber.Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.Targeting GPVI as a novel antithrombotic strategy.Platelets and cancer: a casual or causal relationship: revisited.Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach.Fibrin activates GPVI in human and mouse plateletsAlteration of platelet GPVI signaling in ST-elevation myocardial infarction patients demonstrated by a combination of proteomic, biochemical, and functional approaches.Primary haemostasis: newer insights.Antiplatelet drugs: which targets for which treatments?Ibrutinib-associated bleeding: pathogenesis, management and risk reduction strategies.Clinical significance of receptor shedding-platelet GPVI as an emerging diagnostic and therapeutic tool.Basic mechanisms of platelet receptor shedding.Platelet "first responders" in wound response, cancer, and metastasis.Decreased levels of platelet-derived soluble glycoprotein VI detected prior to the first diagnosis of coronary artery disease in HIV-positive individuals.Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies.ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions.The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents.Post-translational modification of type IV collagen with 3-hydroxyproline affects its interactions with glycoprotein VI and nidogens 1 and 2.Immobilized fibrinogen activates human platelets through glycoprotein VI.Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation.Role of platelets and platelet receptors in cancer metastasis
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The future of glycoprotein VI as an antithrombotic target.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
The future of glycoprotein VI as an antithrombotic target.
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type
label
The future of glycoprotein VI as an antithrombotic target.
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prefLabel
The future of glycoprotein VI as an antithrombotic target.
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P2093
P2860
P50
P356
P1476
The future of glycoprotein VI as an antithrombotic target
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P2093
P2860
P304
P356
10.1111/JTH.12009
P577
2012-12-01T00:00:00Z