The genetic and epigenetic basis of type 2 diabetes and obesity.
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Epigenetic Activation of Wnt/β-Catenin Signaling in NAFLD-Associated HepatocarcinogenesisDissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing toolsGenomics, personalized medicine, and pediatricsDevelopmental origins of obesity and type 2 diabetes: molecular aspects and role of chemicalsGenetic and epigenetic control of metabolic healthBiomarkers linking PCB exposure and obesityMutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neuronsDifferential DNA methylation of MSI2 and its correlation with diabetic traits.Obesity and diabetes: from genetics to epigenetics.Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgeryβ-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registriesEarly Life Origins of Metabolic Syndrome: The Role of Environmental ToxicantsEpigenetic analyses of the insulin-like growth factor binding protein 1 gene in type 1 diabetes and diabetic nephropathySox5 regulates beta-cell phenotype and is reduced in type 2 diabetesAssociation between prehypertension, metabolic and inflammatory markers, decreased adiponectin and enhanced insulinemia in obese subjects.BCL11A gene DNA methylation contributes to the risk of type 2 diabetes in malesDNA methylation of the LY86 gene is associated with obesity, insulin resistance, and inflammation.The positive association of obesity variants with adulthood adiposity strengthens over an 80-year period: a gene-by-birth year interaction.Design, implementation, and evaluation of a pediatric and adolescent type 2 diabetes management program at a tertiary pediatric center.A Review of Mitochondrial-derived Fatty Acids in Epigenetic Regulation of Obesity and Type 2 DiabetesGenetic determinants of atherosclerosis, obesity, and energy balance in consomic mice.Genetic and epigenetic catalysts in early-life programming of adult cardiometabolic disorders.Response: genome-wide association study identifies two novel Loci with sex-specific effects for type 2 diabetes mellitus and glycemic traits in a korean population (diabetes metab j 2014;38:375-87).Parental history of type 2 diabetes, TCF7L2 variant and lower insulin secretion are associated with incident hypertension. Data from the DESIR and RISC cohorts.MicroRNAs: new players in IBD.Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay populationImpact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes.Familial Aggregation between the 14th and 21st Century and Type 2 Diabetes Risk in an Isolated Dutch Population.Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated lociDo discrimination, residential school attendance and cultural disruption add to individual-level diabetes risk among Aboriginal people in Canada?Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese.Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study.Genetic variation in insulin-induced kinase signalingType 2 diabetes mellitus in relation to global LINE-1 DNA methylation in peripheral blood: a cohort study.Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study.Effect of long-term high-fat diet intake on peripheral insulin sensibility, blood pressure, and renal function in female ratsEpigenetic Mechanisms of the Aging Human Retina.An analysis of age-related loss of skeletal muscle mass and its significance on osteoarthritis in a Korean populationRole of maternal vitamins in programming health and chronic disease.
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The genetic and epigenetic basis of type 2 diabetes and obesity.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
The genetic and epigenetic basis of type 2 diabetes and obesity.
@en
type
label
The genetic and epigenetic basis of type 2 diabetes and obesity.
@en
prefLabel
The genetic and epigenetic basis of type 2 diabetes and obesity.
@en
P2093
P2860
P356
P1476
The genetic and epigenetic basis of type 2 diabetes and obesity.
@en
P2093
C M Lindgren
M I McCarthy
P2860
P304
P356
10.1038/CLPT.2012.149
P407
P577
2012-10-10T00:00:00Z