about
A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent mannerMechanism and synergism in epithelial fluid and electrolyte secretion.Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cellsThe immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFαTargeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.Management of high-grade gliomas in the pediatric patient: Past, present, and future.[18 F]FDG-PET imaging is an early non-invasive pharmacodynamic biomarker for a first-in-class dual MEK/Raf inhibitor, RO5126766 (CH5126766), in preclinical xenograft models.Progress in understanding the pathogenesis of Langerhans cell histiocytosis: back to Histiocytosis X?DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.Targeted therapies and clinical trials in ovarian cancer.BRAF and MEK gene rearrangements in melanoma: implications for targeted therapy.Cyclin-dependent kinases as therapeutic targets in melanoma.Current opinion on optimal systemic treatment for metastatic colorectal cancer: outcome of the ACTG/AGITG expert meeting ECCO 2013.New tumor suppressor CXXC finger protein 4 inactivates mitogen activated protein kinase signaling.
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description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
MEK and RAF inhibitors for BRAF-mutated cancers.
@en
type
label
MEK and RAF inhibitors for BRAF-mutated cancers.
@en
prefLabel
MEK and RAF inhibitors for BRAF-mutated cancers.
@en
P2860
P356
P1476
MEK and RAF inhibitors for BRAF-mutated cancers.
@en
P2860
P356
10.1017/ERM.2012.11
P577
2012-10-12T00:00:00Z