Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery.
about
Targeting α4β2 nicotinic acetylcholine receptors in central nervous system disorders: perspectives on positive allosteric modulation as a therapeutic approach.Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects.The development of novel polypharmacological agents targeting the multiple binding sites of nicotinic acetylcholine receptors.Insights into nicotinic receptor signaling in nicotine addiction: Implications for prevention and treatment.Non-equivalent ligand selectivity of agonist sites in (α4β2)2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy.The additional ACh binding site at the α4(+)/α4(-) interface of the (α4β2)2α4 nicotinic ACh receptor contributes to desensitization.
P2860
Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery.
description
2012 nî lūn-bûn
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name
Allosteric modulators of α4β2 ...... antidepressant drug discovery.
@en
type
label
Allosteric modulators of α4β2 ...... antidepressant drug discovery.
@en
prefLabel
Allosteric modulators of α4β2 ...... antidepressant drug discovery.
@en
P2093
P2860
P356
P1476
Allosteric modulators of α4β2 ...... antidepressant drug discovery.
@en
P2093
Constanza Alcaino
Elena Mantione
Karina New
Simone Mazzaferro
Stefano Micheloni
P2860
P304
P356
10.4155/FMC.12.172
P577
2012-11-01T00:00:00Z