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Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Cardiac alternans and intracellular calcium cycling.Transforming growth factor β2 promotes transcription of COX2 and EP4, leading to a prostaglandin E2-driven autostimulatory loop that enhances virulence of Theileria annulata-transformed macrophagesCalcium/calmodulin-dependent kinase II and nitric oxide synthase 1-dependent modulation of ryanodine receptors during β-adrenergic stimulation is restricted to the dyadic cleftCompartmentation of cAMP signalling in cardiomyocytes in health and disease.Epac proteins: specific ligands and role in cardiac remodelling.Polypharmacology of small molecules targeting the ubiquitin-proteasome and ubiquitin-like systems.Modulation of cyclic nucleotide-mediated cellular signaling and gene expression using photoactivated adenylyl cyclase as an optogenetic toolCaMKII mediates stimulus specificity in early odor preference learning in rats.Depotentiation of intact rat cardiac muscle unmasks an Epac-dependent increase in myofilament Ca(2+) sensitivity.Epac Function and cAMP Scaffolds in the Heart and Lung.Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Epac in cardiac calcium signaling.
@en
type
label
Epac in cardiac calcium signaling.
@en
prefLabel
Epac in cardiac calcium signaling.
@en
P50
P1476
Epac in cardiac calcium signaling
@en
P2093
Ana M Gomez
Frank Lezoualc'h
P304
P356
10.1016/J.YJMCC.2012.11.021
P577
2012-12-07T00:00:00Z