Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.
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Organ-on-a-Chip: New Platform for Biological AnalysisModels and methods for in vitro testing of hepatic gap junctional communicationMaturation of induced pluripotent stem cell derived hepatocytes by 3D-cultureAssessing Concordance of Drug-Induced Transcriptional Response in Rodent Liver and Cultured HepatocytesHepatocyte-ductal transdifferentiation is mediated by reciprocal repression of SOX9 and C/EBPα.Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic SteatosisDonor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.Hepatocytes maintain greater fluorescent bile acid accumulation and greater sensitivity to drug-induced cell death in three-dimensional matrix cultureComparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis.Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis.Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.Engineering a perfusable 3D human liver platform from iPS cells.Potential of regenerative medicine techniques in canine hepatology.Bioartificial livers in vitro and in vivo: tailoring biocomponents to the expanding variety of applications.Advancements in in vitro hepatic models: application for drug screening and therapeutics.Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure.Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.In vitro testing of basal cytotoxicity: Establishment of an adverse outcome pathway from chemical insult to cell death.Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions.Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks.Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.Integrated spatiotemporal-metabolic modelling bridges the gap between metabolism on the cellular level and organ function.Use of Thymidine Kinase Recombinant Adenovirus and Ganciclovir Mediated Mouse Liver Preconditioning for Hepatocyte Xenotransplantation.Recellularization of rat liver: An in vitro model for assessing human drug metabolism and liver biology.In vitro systems: current limitations and future perspectives.Decellularization and Solubilization of Porcine Liver for Use as a Substrate for Porcine Hepatocyte Culture: Method Optimization and Comparison.New physiologically-relevant liver tissue model based on hierarchically cocultured primary rat hepatocytes with liver endothelial cells.Human pluripotent stem cell derived HLC transcriptome data enables molecular dissection of hepatogenesis.A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosisInteraction between Iron Oxide Nanoparticles and HepaRG Cells: A PreliminaryIn VitroEvaluation
P2860
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P2860
Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Primary hepatocyte cultures fo ...... -dedifferentiation strategies.
@en
type
label
Primary hepatocyte cultures fo ...... -dedifferentiation strategies.
@en
prefLabel
Primary hepatocyte cultures fo ...... -dedifferentiation strategies.
@en
P2093
P2860
P1476
Primary hepatocyte cultures fo ...... -dedifferentiation strategies.
@en
P2093
P2860
P2888
P304
P356
10.1007/S00204-012-0983-3
P577
2012-12-15T00:00:00Z
P5875
P6179
1000685935