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VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damagemRNA 3'end processing: A tale of the tail reaches the clinicCancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in CancerPancreatic Cancer from Molecular Pathways to Treatment OpinionChe-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 ProteinsMutant p53 Drives Cancer by Subverting Multiple Tumor Suppression PathwaysTargeting Oncogenic Mutant p53 for Cancer Therapyp73: a Positive or Negative Regulator of Angiogenesis, or Both?The Contrived Mutant p53 Oncogene - Beyond Loss of FunctionsMolecular targets for the treatment of pancreatic cancer: Clinical and experimental studiesNovel endogenous angiogenesis inhibitors and their therapeutic potentialDirect and Propagated Effects of Small Molecules on Protein-Protein Interaction NetworksDNA damage response and prostate cancer: defects, regulation and therapeutic implicationsTargeting BCL2-Proteins for the Treatment of Solid TumoursThe other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axisA clinicopathological review of 33 patients with vulvar melanoma identifies c-KIT as a prognostic markerRadiation-Induced Bystander Response: Mechanism and Clinical ImplicationsTumor suppressor p53 and its gain-of-function mutants in cancerWhen heat casts a spell on the DNA damage checkpointsTumor suppressor p53 and its mutants in cancer metabolismSmoking, p53 mutation, and lung cancerThe role of tumor suppressor p53 in the antioxidant defense and metabolismG-actin guides p53 nuclear transport: potential contribution of monomeric actin in altered localization of mutant p53.Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiencyMutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.Caught in the cross fire: p53 in inflammation.Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutationsDifferent prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer.The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) ProdrugsGain of function of mutant p53: R282W on the peak?The role of p53 in cancer drug resistance and targeted chemotherapyChanging perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agentsMdm2 as a chromatin modifierMolecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple MyelomaP53-MDM2 Pathway: Evidences for A New Targeted Therapeutic Approach in B-Acute Lymphoblastic LeukemiaPXR variants: the impact on drug metabolism and therapeutic responsesDysregulation of ubiquitin ligases in cancerHow do oncoprotein mutations rewire protein-protein interaction networks?Control of Oxidative Stress and Generation of Induced Pluripotent Stem Cell-like Cells by Jun Dimerization Protein 2Pathogenic mechanisms of lung adenocarcinoma in smokers and non-smokers determined by gene expression interrogation
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
p53 mutations in cancer.
@en
type
label
p53 mutations in cancer.
@en
prefLabel
p53 mutations in cancer.
@en
P356
P1433
P1476
p53 mutations in cancer.
@en
P2093
Karen H Vousden
Patricia A J Muller
P2888
P356
10.1038/NCB2641
P577
2013-01-01T00:00:00Z
P6179
1029264428