Serotype-independent method of recombinant adeno-associated virus (AAV) vector production and purification.
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Scalable downstream strategies for purification of recombinant adeno- associated virus vectors in light of the properties.MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain.Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model.Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vectorFusion of Human Fetal Mesenchymal Stem Cells with "Degenerating" Cerebellar Neurons in Spinocerebellar Ataxia Type 1 Model Mice.Treatment of hypophosphatasia by muscle-directed expression of bone-targeted alkaline phosphatase via self-complementary AAV8 vector.Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization modelRational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells.Optimized AAV rh.10 Vectors That Partially Evade Neutralizing Antibodies during Hepatic Gene Transfer.Viral Vector-Based Evaluation of Regulatory Regions in the Neuron-Specific Enolase (NSE) Promoter in Mouse Cerebellum In Vivo.miR-15b mediates oxaliplatin-induced chronic neuropathic pain through BACE1 down-regulation.Tyrosine triple mutated AAV2-BDNF gene therapy in a rat model of transient IOP elevation.Inexpensive, serotype-independent protocol for native and bioengineered recombinant adeno-associated virus purification.Inflammation-induced reversible switch of the neuron-specific enolase promoter from Purkinje neurons to Bergmann glia.Transduction Profile of the Marmoset Central Nervous System Using Adeno-Associated Virus Serotype 9 Vectors.Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF.Long-term correction of biochemical and neurological abnormalities in MLD mice model by neonatal systemic injection of an AAV serotype 9 vector.Mutant ataxin-3 with an abnormally expanded polyglutamine chain disrupts dendritic development and metabotropic glutamate receptor signaling in mouse cerebellar Purkinje cells.Ultrafiltered recombinant AAV8 vector can be safely administered in vivo and efficiently transduces liver.
P2860
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P2860
Serotype-independent method of recombinant adeno-associated virus (AAV) vector production and purification.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Serotype-independent method of ...... r production and purification.
@en
type
label
Serotype-independent method of ...... r production and purification.
@en
prefLabel
Serotype-independent method of ...... r production and purification.
@en
P2093
P356
P1476
Serotype-independent method of ...... r production and purification.
@en
P2093
Koichi Miyake
Noriko Miyake
Takashi Shimada
Yoshiyuki Yamazaki
Yukihiko Hirai
P304
P356
10.1272/JNMS.79.394
P577
2012-01-01T00:00:00Z