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Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathwayAdaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsAlpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons DiseaseGlycoprotein Quality Control and Endoplasmic Reticulum StressInside-out neuropharmacology of nicotinic drugsEndoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseasesThe Progressive BSSG Rat Model of Parkinson's: Recapitulating Multiple Key Features of the Human DiseaseFunctional Role of the Disulfide Isomerase ERp57 in Axonal RegenerationInteractions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseControl of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Pharmacotherapies for Parkinson's disease symptoms related to cholinergic degeneration.Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson's disease modelGenetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans.Endoplasmic reticulum stress and inflammation in the central nervous systemDissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network BiologyEndoplasmic reticulum stress and oxidative stress in cell fate decision and human disease.α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP productionCDK5-mediated phosphorylation of XBP1s contributes to its nuclear translocation and activation in MPP+-induced Parkinson's disease modelDeficits in cholinergic neurotransmission and their clinical correlates in Parkinson's disease.Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons.Genome-scale modeling of the protein secretory machinery in yeastTranscriptional regulation by nicotine in dopaminergic neurons.Fibroblast growth factor 1attenuates 6-hydroxydopamine-induced neurotoxicity: an in vitro and in vivo investigation in experimental models of parkinson's disease.Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?Selenotranscriptomic Analyses Identify Signature Selenoproteins in Brain Regions in a Mouse Model of Parkinson's Disease.Leishmania infantum Induces Mild Unfolded Protein Response in Infected Macrophages.Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease.Bent out of shape: α-Synuclein misfolding and the convergence of pathogenic pathways in Parkinson's disease.Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons.Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's diseaseCadmium and Secondary Structure-dependent Function of a Degron in the Pca1p Cadmium Exporter.Inhibition of Endoplasmic Reticulum Stress is Involved in the Neuroprotective Effect of bFGF in the 6-OHDA-Induced Parkinson's Disease Model.Gene Therapy: A Promising Approach for Neuroprotection in Parkinson's Disease?Elevated mitochondria-coupled NAD(P)H in endoplasmic reticulum of dopamine neurons.Bibenzyl compound 20c protects against endoplasmic reticulum stress in tunicamycin-treated PC12 cells in vitroTargeting the unfolded protein response in disease.Parallel mechanisms for direct and indirect membrane protein trafficking by synucleins.Endoplasmic reticulum stress in drug- and environmental toxicant-induced liver toxicity.Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
An ERcentric view of Parkinson's disease.
@en
type
label
An ERcentric view of Parkinson's disease.
@en
prefLabel
An ERcentric view of Parkinson's disease.
@en
P2093
P1476
An ERcentric view of Parkinson's disease.
@en
P2093
Claudio Hetz
Gabriela Mercado
Pamela Valdés
P304
P356
10.1016/J.MOLMED.2012.12.005
P577
2013-01-24T00:00:00Z