Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation.
about
Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domainUSP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradationCleaning up in the endoplasmic reticulum: ubiquitin in chargeInteractome profile of the host cellular proteins and the nonstructural protein 2 of porcine reproductive and respiratory syndrome virusSolution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4AThe final moments of misfolded proteins en route to the proteasome.Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex.Selective Binding of AIRAPL Tandem UIMs to Lys48-Linked Tri-Ubiquitin ChainsA ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradationPeroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomainsMsp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins.UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation.Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis.A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition.Multiple selection filters ensure accurate tail-anchored membrane protein targeting.BAG6 regulates the quality control of a polytopic ERAD substrate.Overexpression of BAT3 alleviates prion protein fragment PrP106-126-induced neuronal apoptosis.SGTA interacts with the proteasomal ubiquitin receptor Rpn13 via a carboxylate clamp mechanism.Elimination of a signal sequence-uncleaved form of defective HLA protein through BAG6.An essential role of intestinal cell kinase in lung development is linked to the perinatal lethality of human ECO syndrome.Orientia tsutsugamushi modulates endoplasmic reticulum-associated degradation to benefit its growth.Heat Shock Protein A2 (HSPA2): Regulatory Roles in Germ Cell Development and Sperm Function.Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells.Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission.
P2860
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P2860
Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Bag6/Bat3/Scythe: a novel chap ...... in biogenesis and degradation.
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type
label
Bag6/Bat3/Scythe: a novel chap ...... in biogenesis and degradation.
@en
prefLabel
Bag6/Bat3/Scythe: a novel chap ...... in biogenesis and degradation.
@en
P2860
P356
P1433
P1476
Bag6/Bat3/Scythe: a novel chap ...... ein biogenesis and degradation
@en
P2093
P2860
P304
P356
10.1002/BIES.201200159
P407
P50
P577
2013-02-18T00:00:00Z