Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
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The role of drug transporters in the kidney: lessons from tenofovirMATE2 Expression Is Associated with Cancer Cell Response to MetforminImmunohistochemical localization of OCT2 in the cochlea of various species.The Concise Guide to PHARMACOLOGY 2013/14: transporters.The role of genetic factors and kidney and liver function in glycemic control in type 2 diabetes patients on long-term metformin and sulphonylurea cotreatment.Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins.A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity.Detecting Renal Allograft Inflammation Using Quantitative Urine Metabolomics and CXCL10.Nuclear Receptors in Drug Metabolism, Drug Response and Drug Interactions.Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice.Small molecule membrane transporters in the mammalian podocyte: a pathogenic and therapeutic target.Drug transporters in the central nervous system.Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine.Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics.Novel compound, organic cation transporter 3 detection agent and organic cation transporter 3 activity inhibitor, WO2015002150 A1: a patent evaluation.Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate.Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines.Investigation on pharmacokinetics, tissue distribution and excretion of a novel platinum anticancer agent in rats by inductively coupled plasma mass spectrometry (ICP-MS).Potent inhibition of human organic cation transporter 2 (hOCT2) by β-carboline alkaloids.Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters.Impact of Substrate-Dependent Inhibition on Renal Organic Cation Transporters hOCT2 and hMATE1/2-K-Mediated Drug Transport and Intracellular Accumulation.MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells.Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine.MDR1 and BCRP Transporter-Mediated Drug-Drug Interaction between Rilpivirine and Abacavir and Effect on Intestinal Absorption.The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent.Histamine Clearance Through Polyspecific Transporters in the Brain.Drug Interactions of Metformin Involving Drug Transporter Proteins.Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.Interaction of green tea catechins with renal organic cation transporter 2.The Role of the Kidney in Drug Elimination: Transport, Metabolism, and the Impact of Kidney Disease on Drug Clearance.Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO).
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Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
@en
type
label
Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
@en
prefLabel
Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
@en
P2860
P1433
P1476
Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
@en
P2093
Hideyuki Motohashi
Ken-ichi Inui
P2860
P2888
P304
P356
10.1208/S12248-013-9465-7
P407
P577
2013-02-22T00:00:00Z
P6179
1020742536