Targeting the unactivated conformations of protein kinases for small molecule drug discovery.
about
Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growthMolecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitorsPhosphate binding by a novel Zn(II) complex featuring a trans-1,2-diaminocyclohexane ligand. Effective anion recognition in water.Bruton's TK inhibitors: structural insights and evolution of clinical candidates.Targeting the DFG-in kinase conformation: a new trend emerging from a patent analysis.Ribosomal S6 kinase (RSK) modulators: a patent review.How Diverse Are the Protein-Bound Conformations of Small-Molecule Drugs and Cofactors?
P2860
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P2860
Targeting the unactivated conformations of protein kinases for small molecule drug discovery.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Targeting the unactivated conf ...... small molecule drug discovery.
@en
type
label
Targeting the unactivated conf ...... small molecule drug discovery.
@en
prefLabel
Targeting the unactivated conf ...... small molecule drug discovery.
@en
P2860
P356
P1476
Targeting the unactivated conf ...... small molecule drug discovery.
@en
P2093
Elizabeth A Lunney
Gordon R Alton
P2860
P304
P356
10.1517/17460441.3.6.595
P407
P577
2008-06-01T00:00:00Z