The SLC16 gene family - structure, role and regulation in health and disease.
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Lactate transport and signaling in the brain: potential therapeutic targets and roles in body-brain interactionGenetic disorders of thyroid metabolism and brain developmentImmunometabolism in TuberculosisThe cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinasesGenetic mechanisms of bone digestion and nutrient absorption in the bone-eating worm Osedax japonicus inferred from transcriptome and gene expression analysesModeling Alveolar Soft Part Sarcomagenesis in the Mouse: A Role for Lactate in the Tumor MicroenvironmentIdentification of novel inhibitors of the amino acid transporter B0 AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes.Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumorsCharacterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization.A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression.Adaptive thermogenesis in white adipose tissue: is lactate the new brown(ing)?Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia.Analysis of the binding moiety mediating the interaction between monocarboxylate transporters and carbonic anhydrase IIGenetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infectionIncreased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.Placental accommodations for transport and metabolism during intra-uterine crowding in pigsTranscriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq.Monocarboxylate transporter 1 inhibitors as potential anticancer agentsDisruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 statusChloride Cotransporters as a Molecular Mechanism underlying Spreading Depolarization-Induced Dendritic BeadingAMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts.Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney.Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle.Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation.Targeting lactate transport suppresses in vivo breast tumour growthMitochondrial Metabolism as a Treatment Target in Anaplastic Thyroid Cancer.Mathematical modeling of acid-base physiology.Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs.Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction.A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamineMetabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness.Prognostic significance of monocarboxylate transporter expression in oral cavity tumors.Monocarboxylate transporters in the brain and in cancer.Acute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms.Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscleGlycolysis and oxidative phosphorylation in neurons and astrocytes during network activity in hippocampal slices.Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate.Hepatitis B virus X protein influences enrichment profiles of H3K9me3 on promoter regions in human hepatoma cell linesRegulation and roles of bicarbonate transporters in cancer.
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P2860
The SLC16 gene family - structure, role and regulation in health and disease.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The SLC16 gene family - structure, role and regulation in health and disease.
@en
type
label
The SLC16 gene family - structure, role and regulation in health and disease.
@en
prefLabel
The SLC16 gene family - structure, role and regulation in health and disease.
@en
P1476
The SLC16 gene family - structure, role and regulation in health and disease.
@en
P2093
Andrew P Halestrap
P304
P356
10.1016/J.MAM.2012.05.003
P577
2013-04-01T00:00:00Z