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Protective effect of ligustrazine on lumbar intervertebral disc degeneration of rats induced by prolonged upright postureMicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cellsCollagen-derived N-acetylated proline-glycine-proline upregulates the expression of pro-inflammatory cytokines and extracellular matrix proteases in nucleus pulposus cells via the NF-κB and MAPK signaling pathways.Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer.Beta1 integrin inhibits apoptosis induced by cyclic stretch in annulus fibrosus cells via ERK1/2 MAPK pathway.Association between TRAIL gene polymorphisms and the susceptibility and severity of lumbar disc degenerationStatic axial overloading primes lumbar caprine intervertebral discs for posterior herniation.RASSF7 expression and its regulatory roles on apoptosis in human intervertebral disc degeneration.SDF‑1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF‑κB pathway.Microarray analysis of genes and gene functions in disc degeneration.Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo.ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration.Responses and adaptations of intervertebral disc cells to microenvironmental stress: a possible central role of autophagy in the adaptive mechanism.Effects of CCN3 on rat cartilage endplate chondrocytes cultured under serum deprivation in vitroIntervertebral Disk Degeneration and Repair.Molecular mechanisms of cell death in intervertebral disc degeneration (Review).Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence.Tumor necrosis factor-α: a key contributor to intervertebral disc degeneration.The roles and perspectives of microRNAs as biomarkers for intervertebral disc degeneration.Insulin-like growth factor 1 antagonizes lumbar disc degeneration through enhanced autophagy.The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress.Activation of autophagy via Ca(2+)-dependent AMPK/mTOR pathway in rat notochordal cells is a cellular adaptation under hyperosmotic stress.Metformin Improves Functional Recovery After Spinal Cord Injury via Autophagy Flux Stimulation.Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture modelLentiviral-mediated RNAi targeting caspase-3 inhibits apoptosis induced by serum deprivation in rat endplate chondrocytes in vitro.Role of autophagy in cell-penetrating peptide transfection model.* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments.TRAIL gene 1595C/T polymorphisms contribute to the susceptibility and severity of intervertebral disc degeneration: a data synthesis.Mesenchymal stem cells deliver exogenous miR-21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration.Association of COL1A1 rs1800012 polymorphism with musculoskeletal degenerative diseases: a meta-analysis.Inflammatory cytokines induce caveolin-1/β-catenin signalling in rat nucleus pulposus cell apoptosis through the p38 MAPK pathway.Circular RNA VMA21 protects against intervertebral disc degeneration through targeting miR-200c and X linked inhibitor-of-apoptosis protein.Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the TLR2/JNK/mitochondrial-mediated pathway.Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation.Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway.Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture.Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS.RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death.Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration.Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Cell death in intervertebral disc degeneration.
@en
type
label
Cell death in intervertebral disc degeneration.
@en
prefLabel
Cell death in intervertebral disc degeneration.
@en
P2093
P2860
P1433
P1476
Cell death in intervertebral disc degeneration.
@en
P2093
Li-ming Xiong
Zeng-wu Shao
P2860
P2888
P304
P356
10.1007/S10495-013-0839-1
P577
2013-07-01T00:00:00Z