Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.
about
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule ProbesRevisiting the sphingolipid rheostat: Evolving concepts in cancer therapySphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyondLipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic TargetsDisruption of G-protein γ5 subtype causes embryonic lethality in miceImpedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurementsHost endothelial S1PR1 regulation of vascular permeability modulates tumor growthSphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.Lysophospholipid receptor nomenclature review: IUPHAR Review 8.Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond.Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactionsImmunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay.Sphingosine 1-Phosphate Receptor 2 and 3 Mediate Bone Marrow-Derived Monocyte/Macrophage Motility in Cholestatic Liver Injury in Mice.Serum-Sphingosine-1-Phosphate Concentrations Are Inversely Associated with Atherosclerotic Diseases in Humans.Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction.S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplificationA sphingosine 1-phosphate receptor 2 selective allosteric agonist.FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines.Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo.The role of sphingosine-1 phosphate and ceramide-1 phosphate in trafficking of normal stem cells and cancer cellsInfluenza viral manipulation of sphingolipid metabolism and signaling to modulate host defense system.G protein-coupled receptors in rheumatology.Sphingosine-1-phosphate metabolism: A structural perspective.S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1β or Lipocalin-2.Fingolimod Exerts only Temporary Antiepileptogenic Effects but Longer-Lasting Positive Effects on Behavior in the WAG/Rij Rat Absence Epilepsy Model.The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro.Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism.Metabolic Regulation of Apoptosis in Cancer.Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages.Reduction of Pertussis Inflammatory Pathology by Therapeutic Treatment With Sphingosine-1-Phosphate Receptor Ligands by a Pertussis Toxin-Insensitive Mechanism.The role of endothelial lipase in lipid metabolism, inflammation, and cancer.Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation.Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection.Sphingosine kinase 1 inhibition improves lipopolysaccharide/D-galactosamine-induced acute liver failure by inhibiting mitogen-activated protein kinases pathway.Organization and Dynamics of Receptor Proteins in a Plasma Membrane.Sphingosine kinase 1 regulates measles virus replication.FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P(3) and phosphoinositide 3-kinase.Progression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signaling
P2860
Q26829985-40A0C60C-5A5A-4DF6-80D8-6E01AA3F59BAQ26996672-45A7A95B-63EC-42B1-B022-B7DE3055051BQ27011857-1E065DCF-A5BD-4B99-906C-0DB1CDF34275Q28276574-90E8A3F8-DBEC-4B57-8B72-838D4CF2A758Q28509591-5948CBCA-0F9B-4824-A7CA-ED5C508B54FBQ30373402-BDAD0342-D3D3-4EAE-8DF9-0CC9CFFBB724Q30582575-D3384087-ECD5-424B-940E-B5A99D25BA4EQ33753317-A1967662-1EAD-4AE3-A75A-73A5A7EE5BB3Q33887756-02148BB2-8420-42A5-AD8C-AB491040BB61Q34025135-0C2896CD-F2DF-4F98-B790-2F5E5C3D0905Q34364844-B6B1EAA9-8EBB-4874-B245-99DF3A1E3F9BQ34565310-9DF50B85-DA88-4DCC-9F2E-6F48FBFCDB69Q34995628-06DC0711-265B-4D96-A648-325A2949AF76Q36012100-2165E8F1-6CDB-4524-B6A0-DF2048D06FF3Q36223845-D4F76418-750D-46E1-8AC1-5B751B2246B1Q36432399-BCF293DC-1EC8-466B-BD90-E6ADA72CD77CQ36563415-3C79F3E1-6B18-4946-B8FD-53DC4E07E7C2Q37205972-3E7FACFA-6DBB-4B31-AC63-EDD659CB933DQ37657227-4179811A-C7B9-40D0-903B-DC1947C675C0Q37726630-8C8D63E1-F6B0-4D16-A0B9-13A63517A1F6Q38159721-521CE472-5F12-4463-A270-8D0833BCE39AQ38199691-D038AC25-9CCE-4A10-86F3-AA0B1ADF0C7AQ38209549-8CF087F0-4143-4DB8-A871-3332AE945194Q38448843-8E566E8A-E9E1-4FC9-874D-BF3ED838ACC5Q38626918-D49F1246-C0E1-446B-B63C-ED8A08575EB2Q38707729-9D8591AD-DBF6-4E5C-BF7E-3C1636E0627FQ38739843-ADEE971A-786A-43CB-A459-4A77F87F2F82Q38915115-14DB88BB-E398-4B82-A716-55E29972B892Q38969211-D841D762-86C2-407C-8F02-C31475AF27C2Q38981282-BD792121-2A5C-41DC-8ED4-9DA34CA48132Q39213750-C0030901-B06E-482B-AFC9-4FC866368574Q39328275-9975669F-26E7-4CC2-9013-A1BF2CCC49C5Q39402889-623D77E5-0618-4A91-AA69-15D29EE019CBQ39655996-9576DC47-7F47-49C1-BB91-0B98DC3050E2Q40165434-30680376-DC64-434D-B2B3-E049B5ABFBB6Q41228347-3E8E928D-409C-4E56-90ED-FD2627E07B10Q41462931-6C754EF8-3850-42BA-BF24-36FC649402B3Q41934199-3F40BA0E-25EC-4B56-9EE7-6BA6A4D32367Q41996678-9039FAD5-1DA6-4EEC-94C7-466DCC9E756DQ42291845-766713ED-1523-482F-A44D-6F050683B398
P2860
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.
@en
type
label
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.
@en
prefLabel
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.
@en
P2093
P1476
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence.
@en
P2093
Edward Roberts
Hugh Rosen
Michael B A Oldstone
Michael Hanson
P304
P356
10.1146/ANNUREV-BIOCHEM-062411-130916
P577
2013-03-18T00:00:00Z