Biologic agents in osteoarthritis: hopes and disappointments. - Wikidata - awgldk - TriplyDB

Biologic agents in osteoarthritis: hopes and disappointments.

Biologic agents in osteoarthritis: hopes and disappointments.

http://www.wikidata.org/entity/Q38094906

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Emerging regulators of the inflammatory process in osteoarthritis Osteoarthritis joint pain: the cytokine connection Anti-inflammatory strategies in cartilage repair Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis.Management of Osteoarthritis with Avocado/Soybean Unsaponifiables.Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening.Lost but making progress--Where will new analgesic drugs come from?Interleukin-1β and tumor necrosis factor-α increase stiffness and impair contractile function of articular chondrocytes.Intra-articular transplantation of atsttrin-transduced mesenchymal stem cells ameliorate osteoarthritis development.Emerging targets in osteoarthritis therapy.Biologic basis of osteoarthritis: state of the evidence Weekly injections of Hylan G-F 20 delay cartilage degeneration in partial meniscectomized rat knees White blood cell concentration correlates with increased concentrations of IL-1ra and improvement in WOMAC pain scores in an open-label safety study of autologous protein solution.Advantages of Pure Platelet-Rich Plasma Compared with Leukocyte- and Platelet-Rich Plasma in Treating Rabbit Knee Osteoarthritis.Age affects joint space narrowing in patients with early active rheumatoid arthritis.Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes.New and emerging treatments for osteoarthritis management: will the dream come true with personalized medicine?Therapeutic targets for rheumatoid arthritis: Progress and promises.The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1: occurrence and potential role in osteoarthritis.Amelioration of human osteoarthritis symptoms with topical 'biotherapeutics': a phase I human trial.Inflammation (or synovitis)-driven osteoarthritis: an opportunity for personalizing prognosis and treatment?An update on the up and coming therapies to treat osteoarthritis, a multifaceted disease.LC-MS/MS analysis and evaluation of the anti-inflammatory activity of components from BushenHuoxue decoction.Biologics in the treatment of chronic pain: a new era of therapy?Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis.Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane Statin use and osteoarthritis. The authors’ reply Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage.Nitric Oxide Dependent Degradation of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Implications for Intra-Articular Delivery.Fibroblast Growth Factor Receptor 3 Inhibits Osteoarthritis Progression in the Knee Joints of Adult Mice.Fractalkine (CX3CL1): a biomarker reflecting symptomatic severity in patients with knee osteoarthritis.CCL17 blockade as a therapy for osteoarthritis pain and disease.Influence of osteoarthritis grade on molecular signature of human cartilage.Bi-directional regulation of cartilage metabolism by inhibiting BET proteins-analysis of the effect of I-BET151 on human chondrocytes and murine joints.Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells.The Role of Vitamin E in Preventing and Treating Osteoarthritis - A Review of the Current Evidence MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12 Onset and Progression of Human Osteoarthritis-Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage?

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Biologic agents in osteoarthritis: hopes and disappointments.

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Biologic agents in osteoarthritis: hopes and disappointments.

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Biologic agents in osteoarthritis: hopes and disappointments.

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Biologic agents in osteoarthritis: hopes and disappointments.

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NRRHEUM.2013.44

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Nature Reviews Rheumatology

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Biologic agents in osteoarthritis: hopes and disappointments.

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Florent Eymard

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Pascal Richette

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Xavier Chevalier

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OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines.

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American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee.

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nrrheum.2013.44

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