Implementing personalized cancer genomics in clinical trials.
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Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine TrialsPrecision medicine for cancer with next-generation functional diagnosticsNext-generation sequencing: hype and hope for development of personalized radiation therapy?Mast cells as a potential prognostic marker in prostate cancerNavigating the rapids: the development of regulated next-generation sequencing-based clinical trial assays and companion diagnosticsBioinformatics for precision medicine in oncology: principles and application to the SHIVA clinical trialEuropean Medicines Agency initiatives and perspectives on pharmacogenomicsMolecular pathology - the value of an integrative approachThe possibility of clinical sequencing in the management of cancerGeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical TrialsPragmatic medicine in solid cancer: a translational alternative to precision medicineComparison of the cancer gene targeting and biochemical selectivities of all targeted kinase inhibitors approved for clinical useIntegrative network modeling approaches to personalized cancer medicineFrom Molecules to Patients: The Clinical Applications of Translational BioinformaticsStrategies for modern biomarker and drug development in oncology.High-Performance Integrated Virtual Environment (HIVE) Tools and Applications for Big Data Analysis.The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data.Biological data sciences in genome research.A new molecular signature method for prediction of driver cancer pathways from transcriptional data.A Scalable Data Access Layer to Manage Structured Heterogeneous Biomedical Data.Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new co-clinical model for treatment optimization.Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell linesGenomic Analysis as the First Step toward Personalized Treatment in Renal Cell CarcinomaClinical implementation of germ line cancer pharmacogenetic variants during the next-generation sequencing era.Liquid biopsy: monitoring cancer-genetics in the blood.Transcriptome interrogation of human myometrium identifies differentially expressed sense-antisense pairs of protein-coding and long non-coding RNA genes in spontaneous labor at term.Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research.High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer.Next-generation sequencing in clinical oncology: next steps towards clinical validationAurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy.Application of molecular profiling in clinical trials for advanced metastatic cancers.Molecularly targeted therapies in non-small-cell lung cancer annual update 2014Mung bean nuclease treatment increases capture specificity of microdroplet-PCR based targeted DNA enrichmentA systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.New concepts in breast cancer genomics and geneticsTop2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer.Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome SequencingBoosting for high-dimensional two-class prediction.Personalized targeted therapy for esophageal squamous cell carcinoma.
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P2860
Implementing personalized cancer genomics in clinical trials.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Implementing personalized cancer genomics in clinical trials.
@en
type
label
Implementing personalized cancer genomics in clinical trials.
@en
prefLabel
Implementing personalized cancer genomics in clinical trials.
@en
P2860
P356
P1476
Implementing personalized cancer genomics in clinical trials.
@en
P2093
Richard Simon
Sameek Roychowdhury
P2860
P2888
P304
P356
10.1038/NRD3979
P577
2013-05-01T00:00:00Z