Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription.
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The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disordersThe bowel and beyond: the enteric nervous system in neurological disordersPitt-Hopkins Syndrome and Differential Diagnosis: A Molecular and Clinical ChallengeWhole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype.Epilepsy and Autism.The second brain in autism spectrum disorder: could connexin 43 expressed in enteric glial cells play a role?Differential Sox10 genomic occupancy in myelinating glia.Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless.DNA methylation and its implications and accessibility for neuropsychiatric therapeutics.Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1Nucleolar Enrichment of Brain Proteins with Critical Roles in Human Neurodevelopment.A case of Pitt-Hopkins syndrome presented with Angelman-like syndromic phenotypesOsteopathic Manipulative Treatment Limits Chronic Constipation in a Child with Pitt-Hopkins Syndrome.The roles of HLH transcription factors in epithelial mesenchymal transition and multiple molecular mechanisms.Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective.An adapted walking intervention for a child with Pitt Hopkins syndrome.Genetic Approaches to Understanding Psychiatric Disease.Drugging the methylome: DNA methylation and memory.Pitt-Hopkins Mouse Model has Altered Particular Gastrointestinal Transits In Vivo.The utility of Next Generation Sequencing for molecular diagnostics in Rett syndrome.Neurodevelopmental models of transcription factor 4 deficiency converge on a common ion channel as a potential therapeutic target for Pitt Hopkins syndromeDe novo nonsense and frameshift variants of TCF20 in individuals with intellectual disability and postnatal overgrowth.Tcf12 Is Involved in Early Cell-Fate Determination and Subset Specification of Midbrain Dopamine Neurons.Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability.Tcf4 transgenic female mice display delayed adaptation in an auditory latent inhibition paradigm.The Intellectual Disability and Schizophrenia Associated Transcription Factor TCF4 Is Regulated by Neuronal Activity and Protein Kinase A.Pitt-Hopkins Syndrome: A Review of Current Literature, Clinical Approach, and 23-Patient Case Series.Prostaglandin E2 promotes neural proliferation and differentiation and regulates Wnt target gene expression.WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene TCF4.5-Hydroxymethylcytosine in E-box motifs ACAT|GTG and ACAC|GTG increases DNA-binding of the B-HLH transcription factor TCF4.Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons.Tcf4 regulates dendritic spine density and morphology in the adult brain.Prioritization of Variants Detected by Next Generation Sequencing According to the Mutation Tolerance and Mutational Architecture of the Corresponding Genes.
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Pitt-Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription.
description
article científic
@ca
article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Pitt-Hopkins Syndrome: intelle ...... -regulated gene transcription.
@en
type
label
Pitt-Hopkins Syndrome: intelle ...... -regulated gene transcription.
@en
prefLabel
Pitt-Hopkins Syndrome: intelle ...... -regulated gene transcription.
@en
P2860
P921
P356
P1476
Pitt-Hopkins Syndrome: intelle ...... 4-regulated gene transcription
@en
P2093
J David Sweatt
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P2888
P356
10.1038/EMM.2013.32
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P577
2013-05-03T00:00:00Z
P5875
P6179
1009780271