The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications.
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AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomasMechanosensing Controlled Directly by Tyrosine Kinases.How to train your dragon: targeted delivery of microRNA to cancer cells in vivo.Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy.Blockade of Axl signaling ameliorates HPV16E6-mediated tumorigenecity of cervical cancer.AXL mediates resistance to cetuximab therapyDifferential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy.Inactivation of GSK3β and activation of NF-κB pathway via Axl represents an important mediator of tumorigenesis in esophageal squamous cell carcinoma.The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcomaThe Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels.Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthmaClinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression.Axl receptor tyrosine kinase expression in breast cancerMesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization.Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome.Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.MicroRNA-432 functions as a tumor suppressor gene through targeting E2F3 and AXL in lung adenocarcinoma.Differential Roles of Carboxylated and Uncarboxylated Osteocalcin in Prostate Cancer Growth.Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer.PSEA: Kinase-specific prediction and analysis of human phosphorylation substrates.Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling.Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo.Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice.ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer typesAXL-associated tumor inflammation as a poor prognostic signature in chemotherapy-treated triple-negative breast cancer patients.AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex.Accuracy of novel diagnostic biomarkers for hepatocellular carcinoma: An update for clinicians (Review)Impact of Concurrent Medication Use on Pancreatic Cancer Survival-SEER-Medicare Analysis.The insulin-like growth factor 1 receptor causes acquired resistance to erlotinib in lung cancer cells with the wild-type epidermal growth factor receptor.AXL receptor tyrosine kinase as a therapeutic target in NSCLC.Targeting AXL overcomes resistance to docetaxel therapy in advanced prostate cancer.Molecular analysis of alternative transcripts of equine AXL receptor tyrosine kinase geneSomatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival.Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms.Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years.Function of Axl receptor tyrosine kinase in non-small cell lung cancer.AXL is a marker for epithelial-mesenchymal transition in esophageal squamous cell carcinoma.Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma.
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The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
The receptor tyrosine kinase A ...... and therapeutic implications.
@en
type
label
The receptor tyrosine kinase A ...... and therapeutic implications.
@en
prefLabel
The receptor tyrosine kinase A ...... and therapeutic implications.
@en
P2860
P356
P1476
The receptor tyrosine kinase A ...... s and therapeutic implications
@en
P2093
M Iqbal Parker
Matjaz Vogelsang
P2860
P304
P356
10.1002/IJC.28246
P577
2013-06-04T00:00:00Z