Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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Neural circuit interactions between the dorsal raphe nucleus and the lateral hypothalamus: an experimental and computational study.

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Q35091506-C8C8C443-9634-4CA3-9DB4-FA8288CCE8BE

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Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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P1476

Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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Artur Pałasz

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Beata Czajkowska

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Damien Lapray

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Ewa Rojczyk-Gołębiewska

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Grzegorz Markowski

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Marek Krzystanek

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Rafał Skowronek

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Ryszard Wiaderkiewicz

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P2860

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

Physiology of the orexinergic/hypocretinergic system: a revisit in 2012

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist

Differential effects of a dual orexin receptor antagonist (SB-649868) and zolpidem on sleep initiation and consolidation, SWS, REM sleep, and EEG power spectra in a model of situational insomnia

The orexin antagonist SB-649868 promotes and maintains sleep in men with primary insomnia

Disposition and metabolism of [14C]SB-649868, an orexin 1 and 2 receptor antagonist, in humans

Orexins in the regulation of the hypothalamic-pituitary-adrenal axis

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

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157-168

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scholarly article

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10.1017/S1461145713000552

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Christelle Peyron

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2013-05-23T00:00:00Z

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23702225

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Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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P2860

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Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698