Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases.
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Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside AnaloguesProdrugs of phosphonates and phosphates: crossing the membrane barrierCapture of a third Mg²⁺ is essential for catalyzing DNA synthesisFUN26 (function unknown now 26) protein from saccharomyces cerevisiae is a broad selectivity, high affinity, nucleoside and nucleobase transporter.Inhibitor-Based Therapeutics for Treatment of Viral HepatitisTelomerase as a Cancer Target. Development of New MoleculesNUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicityTargeted Delivery of Deoxycytidine Kinase to Her2-Positive Cells Enhances the Efficacy of the Nucleoside Analog FludarabineInhibitory Effect of Bridged Nucleosides on Thermus aquaticus DNA Polymerase and Insight into the Binding InteractionsEquilibrative nucleoside transporters-A review.Biophysical Mode-of-Action and Selectivity Analysis of Allosteric Inhibitors of Hepatitis C Virus (HCV) Polymerase.First total synthesis of kipukasin A.Solvatochromic Effects on the Absorption Spectrum of 2-ThiocytosineSynthesis of two fluorescent GTPγS molecules and their biological relevanceA Multidrug-resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy.Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.Synthesis of (carbo)nucleoside analogues by [3+2] annulation of aminocyclopropanes.Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides.Antiviral therapies and prospects for a cure of chronic hepatitis B.DNA repair mechanisms in cancer development and therapyHigh-Throughput Hit Screening Cascade to Identify Respiratory Syncytial Virus (RSV) Inhibitors.Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity.Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf.Synthesis of 6,8,9 poly-substituted purine analogue libraries as pro-apoptotic inducers of human leukemic lymphocytes and DAPK-1 inhibitors.Mycoplasmas and cancer: focus on nucleoside metabolismNucleic Acid Bioconjugates in Cancer Detection and Therapy.The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.A Positive Selection for Nucleoside Kinases in E. coliZika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library.Development of a cancer-marker activated enzymatic switch from the herpes simplex virus thymidine kinase.A multifunctional catalyst that stereoselectively assembles prodrugs.Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate.Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.Metabolic regulation via enzyme filamentationQuantitative Detection of Nucleoside Analogues by Multi-enzyme Biosensors using Time-Resolved Kinetic Measurements.Cladribine and Fludarabine Nucleotides Induce Distinct Hexamers Defining a Common Mode of Reversible RNR Inhibition.Nuclear Receptors in Drug Metabolism, Drug Response and Drug Interactions.The origin of efficient triplet state population in sulfur-substituted nucleobases.Nanoparticles as Drug Delivery Systems in Cancer Medicine: Emphasis on RNAi-Containing Nanoliposomes.DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotides
P2860
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P2860
Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Advances in the development of ...... for cancer and viral diseases.
@en
type
label
Advances in the development of ...... for cancer and viral diseases.
@en
prefLabel
Advances in the development of ...... for cancer and viral diseases.
@en
P2093
P50
P356
P1476
Advances in the development of ...... for cancer and viral diseases
@en
P2093
Charles Dumontet
Fabien Zoulim
Lars Petter Jordheim
P2888
P304
P356
10.1038/NRD4010
P577
2013-06-01T00:00:00Z