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Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor RadiosensitizationNon-canonical signaling mode of the epidermal growth factor receptor familyThe role of endocytic Rab GTPases in regulation of growth factor signaling and the migration and invasion of tumor cellsUnderstanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentHinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cellsEpidermal growth factor receptor targeted nuclear delivery and high-resolution whole cell X-ray imaging of Fe3O4@TiO2 nanoparticles in cancer cells.Prognostic biomarkers in phase II trial of cetuximab-containing induction and chemoradiation in resectable HNSCC: Eastern cooperative oncology group E2303.PGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells.EGFR expression and survival in patients given cetuximab and chemoradiation for stage III non-small cell lung cancer: a secondary analysis of RTOG 0324.Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancerCetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: a retrospective study in a single comprehensive European cancer institution.γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition.Potential crosstalk between cofilin-1 and EGFR pathways in cisplatin resistance of non-small-cell lung cancerEGFR inhibits DNA mismatch repairThe Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the NucleusNuclear localization of epidermal growth factor receptor (EGFR) in ameloblastomas.Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.Cyclooxygenase-2 expression is positively associated with lymph node metastasis in nasopharyngeal carcinoma.Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair SignalingIntra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer.UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathwayA small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4.Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non-Small Cell Lung Cancer Cells.A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases.DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive propertiesEstradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells.Different clinical significance of FGFR1-4 expression between diffuse-type and intestinal-type gastric cancer.WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.Resveratrol mediates cell cycle arrest and cell death in human esophageal squamous cell carcinoma by directly targeting the EGFR signaling pathway.Twist1 Enhances Hypoxia Induced Radioresistance in Cervical Cancer Cells by Promoting Nuclear EGFR Localization.EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple-negative breast carcinomas.FM807, a curcumin analogue, shows potent antitumor effects in nasopharyngeal carcinoma cells by heat shock protein 90 inhibition.Novel roles and therapeutic targets of Epstein-Barr virus-encoded latent membrane protein 1-induced oncogenesis in nasopharyngeal carcinoma.Effects of different ligands on epidermal growth factor receptor (EGFR) nuclear translocationβ-Arrestin-2 Counters CXCR7-Mediated EGFR Transactivation and Proliferation.EGF-modified mPEG-PLGA-PLL nanoparticle for delivering doxorubicin combined with Bcl-2 siRNA as a potential treatment strategy for lung cancer.Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution.Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab.FTS is responsible for radiation-induced nuclear phosphorylation of EGFR and repair of DNA damage in cervical cancer cells.Novel insight into triple-negative breast cancers, the emerging role of angiogenesis, and antiangiogenic therapy.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Nuclear EGFR as a molecular target in cancer.
@en
type
label
Nuclear EGFR as a molecular target in cancer.
@en
prefLabel
Nuclear EGFR as a molecular target in cancer.
@en
P2093
P2860
P1476
Nuclear EGFR as a molecular target in cancer.
@en
P2093
Deric L Wheeler
Evan J Huppert
Megan M Starr
Neha Luthar
Toni M Brand
P2860
P304
P356
10.1016/J.RADONC.2013.06.010
P577
2013-07-03T00:00:00Z