Endothelin 1 in cancer: biological implications and therapeutic opportunities.
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β-arrestin1 at the cross-road of endothelin-1 signaling in cancerG Protein-Coupled Receptors in CancerEndothelinEvaluating the Oxidative Stress in Inflammation: Role of MelatoninInhibition of ENaC by endothelin-1Targeting the tumor vasculature to enhance T cell activityActivation mechanism of endothelin ETB receptor by endothelin-1Optical imaging probes in oncologyCell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by HypoxiaEndothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expressionFunctions of endothelin-1 in apoptosis and migration in hepatocellular carcinoma.Effects of silencing endothelin-1 on invasion and vascular formation in lung cancer.Prostate cancer and bone: the elective affinities.Melatonin for the prevention and treatment of cancerRole of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells.Endothelin-1/endothelin A receptor-mediated biased signaling is a new player in modulating human ovarian cancer cell tumorigenesis.The host microenvironment influences prostate cancer invasion, systemic spread, bone colonization, and osteoblastic metastasis.EZH2 promotes angiogenesis through inhibition of miR-1/Endothelin-1 axis in nasopharyngeal carcinoma.MMPs and angiogenesis affect the metastatic potential of a human vulvar leiomyosarcoma cell line.High SPARC Expression Starting from Dysplasia, Associated with Breast Carcinoma, Is Predictive for Bone Metastasis without Enhancement of Plasma LevelsBCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism.Colon cancer cell invasion is promoted by protein kinase CK2 through increase of endothelin-converting enzyme-1c protein stability.Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in MiceTreatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel.Epigenetic suppression of neprilysin regulates breast cancer invasionmiR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma.Endothelin therapeutics in cancer: Where are we?Disrupting the endothelin and Wnt relationship to overcome chemoresistance.Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression.Salvianolic Acid A, as a Novel ETA Receptor Antagonist, Shows Inhibitory Effects on Tumor in VitroAcquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer.Rendomab B4, a monoclonal antibody that discriminates the human endothelin B receptor of melanoma cells and inhibits their migration.The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment.Endothelin-converting enzyme-1 (ECE-1) is post-transcriptionally regulated by alternative polyadenylationBiased G Protein-Coupled Receptor Signaling: New Player in Modulating Physiology and PathologyPDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signalsThe interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor.Targeted Agents in Preclinical and Early Clinical Development for the Treatment of Cancer Bone Metastases.Endothelin-1 receptor blockade as new possible therapeutic approach in multiple myeloma.
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Endothelin 1 in cancer: biological implications and therapeutic opportunities.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Endothelin 1 in cancer: biological implications and therapeutic opportunities.
@en
type
label
Endothelin 1 in cancer: biological implications and therapeutic opportunities.
@en
prefLabel
Endothelin 1 in cancer: biological implications and therapeutic opportunities.
@en
P2093
P356
P1476
Endothelin 1 in cancer: biological implications and therapeutic opportunities.
@en
P2093
Anna Bagnato
Francesca Spinella
Laura Rosanò
P2888
P304
P356
10.1038/NRC3546
P407
P577
2013-07-25T00:00:00Z
P6179
1035303163