Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field - Wikidata - awgldk - TriplyDB

Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field

Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field

http://www.wikidata.org/entity/Q38150698

about

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication Heteroreceptor Complexes and their Allosteric Receptor-Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug Development The role of transmitter diffusion and flow versus extracellular vesicles in volume transmission in the brain neural-glial networks The triplet puzzle theory indicates extensive formation of heteromers between opioid and chemokine receptor subtypes.Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia.On the role of A₂A and D₂ receptors in control of cocaine and food-seeking behaviors in rats.Role for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures.Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease Systematic protein-protein interaction mapping for clinically relevant human GPCRs Diversity and Bias through Receptor-Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization.Dopamine heteroreceptor complexes as therapeutic targets in Parkinson's disease.Volume Transmission in Central Dopamine and Noradrenaline Neurons and Its Astroglial Targets.Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes.The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.Differential activation of arginine-vasopressin receptor subtypes in the amygdaloid modulation of anxiety in the rat by arginine-vasopressin.Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression.Basimglurant for treatment of major depressive disorder: a novel negative allosteric modulator of metabotropic glutamate receptor 5.Capturing the multiscale dynamics of membrane protein complexes with all-atom, mixed-resolution, and coarse-grained models.Effects of Long-Term Alcohol Drinking on the Dopamine D2 Receptor: Gene Expression and Heteroreceptor Complexes in the Striatum in Rats.The impact of receptor-receptor interactions in heteroreceptor complexes on brain plasticity.Functional role of striatal A2A, D2, and mGlu5 receptor interactions in regulating striatopallidal GABA neuronal transmission.Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation.

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P2860

Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field

http://www.wikidata.org/entity/Q38150698

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Neuropsychopharmacology

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Alexander O Tarakanov

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Luigi F Agnati

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Wilber Romero-Fernandez

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P2860

Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance

Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity

Dopamine D2 receptors form higher order oligomers at physiological expression levels

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes

Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function

Receptor heteromerization and drug discovery.

Building a new conceptual framework for receptor heteromers

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131-155

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scholarly article

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10.1038/NPP.2013.242

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1

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39

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Miklós Palkovits

DASIEL OSCAR BORROTO ESCUELA

Francisco Ciruela

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2013-09-06T00:00:00Z

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G protein-coupled receptor

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