Mechanisms of age-related macular degeneration and therapeutic opportunities. - Wikidata - awgldk - TriplyDB

Mechanisms of age-related macular degeneration and therapeutic opportunities.

Mechanisms of age-related macular degeneration and therapeutic opportunities.

http://www.wikidata.org/entity/Q38150757

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Relationship between Oxidative Stress, Circadian Rhythms, and AMD Contribution of microglia-mediated neuroinflammation to retinal degenerative diseases Optogenetic approaches to retinal prosthesis Geographic Atrophy and Choroidal Neovascularization in the Same Eye: A Review PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression Homocysteine and risk of age-related macular degeneration: a systematic review and meta-analysis.Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration.Failure of intravitreal bevacizumab in the treatment of choroidal metastasis.Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium.Hedgehog Signaling Components Are Expressed in Choroidal Neovascularization in Laser-induced Retinal Lesion Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization.A novel bispecific molecule delivered by recombinant AAV2 suppresses ocular inflammation and choroidal neovascularization The association between statin use and risk of age-related macular degeneration.Tuning the specificity of a Two-in-One Fab against three angiogenic antigens by fully utilizing the information of deep mutational scanning.3H-1,2-dithiole-3-thione protects retinal pigment epithelium cells against Ultra-violet radiation via activation of Akt-mTORC1-dependent Nrf2-HO-1 signaling.Nuclear Factor (Erythroid-Derived)-Related Factor 2-Associated Retinal Pigment Epithelial Cell Protection under Blue Light-Induced Oxidative Stress.SC79 protects retinal pigment epithelium cells from UV radiation via activating Akt-Nrf2 signaling.miRNA-141 attenuates UV-induced oxidative stress via activating Keap1-Nrf2 signaling in human retinal pigment epithelium cells and retinal ganglion cells.Is age-related macular degeneration a manifestation of systemic disease? New prospects for early intervention and treatment.Dietary modification and supplementation for the treatment of age-related macular degeneration.Gene therapy for age-related macular degeneration.Protective effects of resveratrol and its analogs on age-related macular degeneration in vitro.Postprandial dietary fatty acids exert divergent inflammatory responses in retinal-pigmented epithelium cells.Neuro-protective Mechanisms of Lycium barbarum.Squamosamide derivative FLZ inhibits TNF-α-induced ICAM-1 expression via down-regulation of the NF-κB signaling pathway in ARPE-19 cells.Attenuation of EMT in RPE cells and subretinal fibrosis by an RAR-γ agonist.The impact of the human genome project on complex disease Early Age-related Macular Degeneration with Cardiovascular and Renal Comorbidities: An Analysis of the National Health and Nutrition Examination Survey, 2005-2008.Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration.Deep Sequencing-guided Design of a High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular Degeneration.Taxifolin protects RPE cells against oxidative stress-induced apoptosis.RPE Cell and Sheet Properties in Normal and Diseased Eyes Ocular fundus abnormalities in patients with Balkan endemic nephropathy and other chronic kidney diseases.Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide.Simple and complex retinal dystrophies are associated with profoundly different disease networks Abnormal retinal development in Cloche mutant zebrafish Lack of the P2X7 receptor protects against AMD-like defects and microparticle accumulation in a chronic oxidative stress-induced mouse model of AMD.Salubrinal attenuated retinal neovascularization by inhibiting CHOP-HIF1α-VEGF pathways.Mechanical spectroscopy of retina explants at the protein level employing nanostructured scaffolds.

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P2860

Mechanisms of age-related macular degeneration and therapeutic opportunities.

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Mechanisms of age-related macular degeneration and therapeutic opportunities.

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Mechanisms of age-related macular degeneration and therapeutic opportunities.

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Mechanisms of age-related macular degeneration and therapeutic opportunities.

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The Journal of Pathology

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Mechanisms of age-related macular degeneration and therapeutic opportunities.

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Jennifer LeCouter

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Menno van Lookeren Campagne

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P2860

Segmental nature of the choroidal vasculature

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

Susceptibility genes for age-related maculopathy on chromosome 10q26.

VEGF-Trap: a VEGF blocker with potent antitumor effects.

Complement factor H polymorphism in age-related macular degeneration

Variation near complement factor I is associated with risk of advanced AMD

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

Mechanisms of age-related macular degeneration

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151-164

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10.1002/PATH.4266

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2

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2014-01-01T00:00:00Z

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257534774

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24105633

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