Biomarkers of drugs targeting HER-family signalling in cancer.
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Cetuximab Reconstitutes Pro-Inflammatory Cytokine Secretions and Tumor-Infiltrating Capabilities of sMICA-Inhibited NK Cells in HNSCC Tumor Spheroids.Open pipelines for integrated tumor genome profiles reveal differences between pancreatic cancer tumors and cell linesPredictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistanceEvolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyA Meta-Analysis on the Relations between EGFR R521K Polymorphism and Risk of Cancer.Buparlisib , an oral pan-PI3K inhibitor for the treatment of breast cancer.HER4 is a novel prognostic biomarker in gastrointestinal stromal tumor specifically originated from stomach.Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification.The combinatorial approach of laser-captured microdissection and reverse transcription quantitative polymerase chain reaction accurately determines HER2 status in breast cancer.Epistatic interactions and drug response.Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody.Investigational ErbB-2 tyrosine kinase inhibitors for the treatment of breast cancer.EGFR gene mutation in gastrointestinal stromal tumours.Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma.SNP rs3202538 in 3'UTR region of ErbB3 regulated by miR-204 and miR-211 promote gastric cancer development in Chinese population.NanoString nCounter® Approach in Breast Cancer: A Comparative Analysis with Quantitative Real-Time Polymerase Chain Reaction, In Situ Hybridization, and Immunohistochemistry.Predicting response to HER2 kinase inhibition.Breast cancers with EGFR and HER2 co-amplification favor distant metastasis and poor clinical outcome.DUSP4 is associated with increased resistance against anti-HER2 therapy in breast cancer.Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients.Pathology in drug discovery and development.Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers.Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: A report of two instructive cases.Immunoglobulin G fragment C receptor polymorphisms and efficacy of preoperative chemotherapy plus trastuzumab and lapatinib in HER2-positive breast cancer.HER3 protein expression in relation to HER2 positivity in patients with primary colorectal cancer: clinical relevance and prognostic value.
P2860
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P2860
Biomarkers of drugs targeting HER-family signalling in cancer.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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Biomarkers of drugs targeting HER-family signalling in cancer.
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type
label
Biomarkers of drugs targeting HER-family signalling in cancer.
@en
prefLabel
Biomarkers of drugs targeting HER-family signalling in cancer.
@en
P2860
P356
P1476
Biomarkers of drugs targeting HER-family signalling in cancer
@en
P2093
Maurizio Scaltriti
P2860
P304
P356
10.1002/PATH.4269
P577
2014-01-01T00:00:00Z