about
Classic and contemporary approaches to modeling biochemical reactionsDiscovery of Potent and Selective Covalent Inhibitors of JNKThe nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic dataLINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.Adaptive informatics for multifactorial and high-content biological data.Analysis of growth factor signaling in genetically diverse breast cancer linesProfiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines.Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis.Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.Secondary structure in the 5'-leader or 3'-untranslated region reduces protein yield but does not affect the functional interaction between the 5'-cap and the poly(A) tail.A cell cycle phosphoproteome of the yeast centrosome.Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics.Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics.A multi-center study on factors influencing the reproducibility of in vitro drug-response studiesEnabling drug discovery for the PARP protein family through the detection of mono-ADP-ribosylationReceptor-based mechanism of relative sensing and cell memory in mammalian signaling networks
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Mario Niepel
@ast
Mario Niepel
@en
Mario Niepel
@es
Mario Niepel
@nl
Mario Niepel
@sl
type
label
Mario Niepel
@ast
Mario Niepel
@en
Mario Niepel
@es
Mario Niepel
@nl
Mario Niepel
@sl
prefLabel
Mario Niepel
@ast
Mario Niepel
@en
Mario Niepel
@es
Mario Niepel
@nl
Mario Niepel
@sl
P1053
G-5443-2011
P106
P1153
6507662374
P21
P31
P3829
P496
0000-0003-1415-6295