Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling.
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Teratogenic mechanisms of medical drugsSurvey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): a potential source for functional food ingredients and drug formulationsCarbamazepine-provoked hepatotoxicity and possible aetiopathological role of glutathione in the events. Retrospective review of old data and call for new investigation.Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes.Quantitative structure-activity relationships for the developmental toxicity of haloacetic acids in mammalian whole embryo culture.The potential role of redox cycling as a mechanism for chemical teratogenesisOxidative stress in toxicology: established mammalian and emerging piscine model systemsThiram and dimethyldithiocarbamic acid interconversion in Saccharomyces cerevisiae: a possible metabolic pathway under the control of the glutathione redox cycle.Comparison of hydroxyl radical, peroxyl radical, and peroxynitrite scavenging capacity of extracts and active components from selected medicinal plantsDrug metabolism and pharmacokinetics.Pharmacogenetics of drug-induced birth defects: what is known so far?Use of oligonucleotides to define the site of interstrand cross-links induced by Adriamycin.Possible reactive intermediates in the oxidative biotransformation of hexachlorobenzene.Free radical mediated cell toxicity by redox cycling chemicalsBasic concepts in drug metabolism: Part I.Basic concepts in drug metabolism: Part II.Electron paramagnetic resonance study of the generation of reactive oxygen species catalysed by transition metals and quinoid redox cycling by inhalable ambient particulate matter.Metal (Pb, Cd, and Cu)-induced reactive oxygen species accumulations in aerial root cells of the Chinese banyan (Ficus microcarpa).Formation of adriamycin--DNA adducts in vitro.Stability of adriamycin-induced DNA adducts and interstrand crosslinks.Combined effect of epirubicin and lymphokine-activated killer cells on the resistant human breast cancer cells.Regulation of Nramp1 mRNA stability by oxidants and protein kinase C in RAW264.7 macrophages expressing Nramp1(Gly169).Biological effects of menadione photochemistry: effects of menadione on biological systems may not involve classical oxidant production.Free radicals as mediators of tissue injury and disease.Biochemical toxicology of chemical teratogenesis.Reactive oxygen species in developmental toxicity: review and hypothesis.Free radical generating mechanisms in the colon: their role in the induction and promotion of colorectal cancer?Selective inhibition of adenylate cyclase in bovine cortex by quinones: a novel cellular substrate for quinone cytotoxicity.Activation of hepatocyte protein kinase C by redox-cycling quinones.Stimulation of NADH-dependent microsomal DNA strand cleavage by rifamycin SV.Diclofenac-induced biochemical and histopathological changes in white leghorn birds (Gallus domesticus).The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells.Pyridine nucleotide changes in hepatocytes exposed to quinones.Lipid peroxidation as a possible secondary mechanism of sterigmatocystin toxicity.Ascorbic acid, redox cycling, lipid peroxidation, and the binding of dopamine receptor antagonists.Charge transfer-oxy radical mechanism for anticancer agents: mAMSA derivatives, rhodamine 123, and nickel salicylaldoximate.One-electron reduction of mitomycin c by rat liver: role of cytochrome P-450 and NADPH-cytochrome P-450 reductase.Neuroprotective activity of L-theanine on 3-nitropropionic acid-induced neurotoxicity in rat striatum.Assessment of antimutagenic action of Celtis glabrata Steven ex Planch. (Cannabaceae) extracts against base pair exchange and frame shift mutations on Salmonella typhimurium TA98 and TA100 strains by Ames test.Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase.
P2860
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P2860
Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling.
description
article científic
@ca
article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling.
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type
label
Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling.
@en
prefLabel
Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling.
@en
P1476
Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling.
@en
P2093
P356
10.1016/0006-2952(86)90544-7
P407
P577
1986-01-01T00:00:00Z