Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases.
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Role of histone deacetylases in pancreas: Implications for pathogenesis and therapyThe Altered Hepatic Tubulin Code in Alcoholic Liver DiseaseEpigenetic mechanisms of chronic painHistone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammationHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyMetabolic alkene labeling and in vitro detection of histone acylation via the aqueous oxidative Heck reactionThe histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases.Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.Stearoyl-CoA desaturase 1 expression is downregulated in liver and udder during E. coli mastitis through enhanced expression of repressive C/EBP factors and reduced expression of the inducer SREBP1A.Fungal KATs/KDACs: A New Highway to Better Antifungal Drugs?HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity.The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation.Arbitrarily Accessible 3D Microfluidic Device for Combinatorial High-Throughput Drug Screening.Selective class IIa HDAC inhibitors: myth or reality.Histone Modifications and Asthma. The Interface of the Epigenetic and Genetic Landscapes.The nature of the GRE influences the screening for GR-activity enhancing modulators.Epigenetic regulation of cardiac fibrosis.Drugging the pain epigenome.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Valproic Acid Prevents Renal Dysfunction and Inflammation in the Ischemia-Reperfusion Injury Model.Light-Controlled Histone Deacetylase (HDAC) Inhibitors: Towards Photopharmacological Chemotherapy.Molecular structures guide the engineering of chromatin.The histone deacetylase Hdac1 regulates inflammatory signalling in intestinal epithelial cellsThe Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer.Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage.A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices.Butyrate protects against disruption of the blood-milk barrier and moderates inflammatory responses in a model of mastitis induced by lipopolysaccharide.Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids.Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat ArthritisTargeting transcription factor lysine acetylation in inflammatory airway diseasesMechanisms of NF-κB p65 and strategies for therapeutic manipulation
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P2860
Small molecule inhibitors of histone acetyltransferases and deacetylases are potential drugs for inflammatory diseases.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Small molecule inhibitors of h ...... ugs for inflammatory diseases.
@en
type
label
Small molecule inhibitors of h ...... ugs for inflammatory diseases.
@en
prefLabel
Small molecule inhibitors of h ...... ugs for inflammatory diseases.
@en
P1433
P1476
Small molecule inhibitors of h ...... rugs for inflammatory diseases
@en
P2093
Nathaniel I Martin
Thea van den Bosch
P304
P356
10.1016/J.DRUDIS.2013.11.012
P577
2013-11-21T00:00:00Z