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Ruthenium polypyridyl complex inhibits growth and metastasis of breast cancer cells by suppressing FAK signaling with enhancement of TRAIL-induced apoptosis.Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis.The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction.An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer.Focal adhesion kinase overexpression and its impact on human osteosarcoma.Inhibition of integrin β3, a binding partner of kallistatin, leads to reduced viability, invasion and proliferation in NCI-H446 cells.CD151-mediated adhesion is crucial to osteosarcoma pulmonary metastasis.Methionine deprivation suppresses triple-negative breast cancer metastasis in vitro and in vivoCryptomphalus aspersa Mollusc Egg Extract Promotes Regenerative Effects in Human Dermal Papilla Stem Cells.Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression.The extracellular matrix modulates the hallmarks of cancer.Salinomycin exhibits anti-angiogenic activity against human glioma in vitro and in vivo by suppressing the VEGF-VEGFR2-AKT/FAK signaling axis.A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells.Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways.FAK inhibitors in Cancer, a patent review.Differences in p53 status significantly influence the cellular response and cell survival to 1,25-dihydroxyvitamin D3-metformin cotreatment in colorectal cancer cells.PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment.MicroRNA-150 suppresses the growth and malignant behavior of papillary thyroid carcinoma cells via downregulation of MUC4.The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells.Imidazoles as potential anticancer agents
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
@es
name
The role of FAK in tumor metabolism and therapy.
@en
type
label
The role of FAK in tumor metabolism and therapy.
@en
prefLabel
The role of FAK in tumor metabolism and therapy.
@en
P1476
The role of FAK in tumor metabolism and therapy
@en
P2093
Jianliang Zhang
Steven N Hochwald
P304
P356
10.1016/J.PHARMTHERA.2013.12.003
P577
2013-12-09T00:00:00Z