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Potentials of single-cell biology in identification and validation of disease biomarkersUnit testing, model validation, and biological simulationWholeCellSimDB: a hybrid relational/HDF database for whole-cell model predictionsMulti-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coliComplete atomistic model of a bacterial cytoplasm for integrating physics, biochemistry, and systems biology.Robust and efficient parameter estimation in dynamic models of biological systemsData quality in drug discovery: the role of analytical performance in ligand binding assays.Toward Community Standards and Software for Whole-Cell ModelingCurrent advances in systems and integrative biologyIntegrating single-molecule experiments and discrete stochastic models to understand heterogeneous gene transcription dynamics.Parameter estimation in large-scale systems biology models: a parallel and self-adaptive cooperative strategyParameter identifiability analysis and visualization in large-scale kinetic models of biosystemsSynthetic chromosomes.Multi-level and hybrid modelling approaches for systems biologyGenome-scale modelling of microbial metabolism with temporal and spatial resolution.Guidelines for Reproducibly Building and Simulating Systems Biology Models.How to deal with parameters for whole-cell modelling.Potential unsatisfiability of cyclic constraints on stochastic biological networks biases selection towards hierarchical architectures.Emerging whole-cell modeling principles and methods.Integrating transcriptional activity in genome-scale models of metabolism.Bridging the gap between modules in isolation and as part of networks: A systems framework for elucidating interaction and regulation of signalling modules.Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
The future of whole-cell modeling.
@en
type
label
The future of whole-cell modeling.
@en
prefLabel
The future of whole-cell modeling.
@en
P2093
P2860
P1476
The future of whole-cell modeling.
@en
P2093
Derek N Macklin
Markus W Covert
Nicholas A Ruggero
P2860
P304
P356
10.1016/J.COPBIO.2014.01.012
P577
2014-02-17T00:00:00Z